ZOLADEX Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • diabetes
  • angina, a type of chest pain
  • trouble breathing
  • If experienced, these tend to have a Less Severe expression i

  • mood changes
  • altered interest in having sexual intercourse
  • depression
  • the inability to have an erection
  • inflammation or infection of the vagina
  • acne
  • seborrhea
  • joint pain
  • flu-like symptoms
  • excessive sweating
  • headache
  • an inability to completely empty the bladder
  • involuntary leakage of urine
  • high blood sugar
  • reactions at the site of the injection
  • drug-induced hot flashes
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • a type of joint disorder due to excess uric acid in the blood called gout
  • high amount of calcium in the blood
  • anemia
  • high blood pressure
  • abnormal heart rhythm
  • chronic heart failure
  • peripheral vascular disease
  • pneumonia
  • worsening of debilitating chronic lung disease called COPD
  • decreased kidney function
  • osteoporosis, a condition of weak bones
  • bone pain
  • a skin rash
  • If experienced, these tend to have a Less Severe expression i

  • a herpes simplex infection
  • dry eye
  • low blood pressure
  • a common cold
  • constipation
  • urinary tract infection
  • enlarged breasts
  • breast pain
  • breast fullness due to milk production
  • itching
  • hair loss
  • dry skin
  • an abnormal increase in muscle tone
  • muscle pain
  • leg cramps
  • dizziness
  • difficulty sleeping
  • fever
  • low energy
  • pain
  • visible water retention
  • decreased appetite
  • weight gain
  • heart throbbing or pounding
  • cough
  • nausea
  • vomiting
  • diarrhea
  • abdominal bloating
  • pelvic pain
  • a feeling of pins and needles on skin
  • low energy and weakness
  • generalized weakness
  • a feeling of general discomfort called malaise
  • intense abdominal pain
  • anxious feelings
  • pain with sexual intercourse
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • a tumor of the pituitary gland
  • mental problems from taking the drug
  • a heart attack
  • a clot in the lung
  • a stroke
  • blood clot in a deep vein of the extremities
  • bleeding
  • bloody urine
  • an ovarian cyst
  • ovarian hyperstimulation syndrome, an abnormal enlargement of the ovaries
  • hives
  • seizures
  • a significant type of allergic reaction called anaphylaxis
  • obstruction of any part of the urinary tract
  • pituitary gland infarction
  • spinal cord compression
  • sepsis
  • If experienced, these tend to have a Less Severe expression i

  • bruising under the skin
  • dry mouth
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.