PERCOCET Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • low blood pressure

If experienced, these tend to have a Less Severe expression i

  • constipation
  • drowsiness
  • fainting
  • dizziness
  • low energy
  • headache
  • nausea
  • vomiting
  • generalized weakness
  • a feeling of general discomfort called malaise

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • abnormal liver function tests
  • dependence on opioid-type drugs
  • orthostatic hypotension, a form of low blood pressure
  • widening of blood vessels
  • spasm of a bile duct tract

If experienced, these tend to have a Less Severe expression i

  • dry mouth
  • indigestion
  • fever
  • excessive sweating
  • fluid retention in the legs, feet, arms or hands
  • temporary redness of face and neck
  • diarrhea
  • nervousness
  • intense abdominal pain

RARE side effects

If experienced, these tend to have a Severe expression i

  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • vocal cord swelling
  • acute liver failure
  • damage to the liver and inflammation
  • inflammation of the skin due to an allergy
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a type of allergic reaction called angioedema
  • a type of bumpy skin rash called a maculopapular rash
  • a type of skin disorder called acute generalized exanthematous pustulosis
  • decreased function of the adrenal gland
  • adrenal gland problems
  • anemia
  • confusion
  • addiction to a drug
  • depression
  • heart failure
  • thrombophlebitis, an inflamed vein due to a blood clot
  • throat swelling
  • a spasm of the larynx
  • a complete or partial collapse of the lung airways called atelectasis
  • lung failure causing loss of breath
  • decreased lung function
  • bronchospasm
  • blocked bowels with decreased peristaltic movement
  • hives
  • an abnormal increase in muscle tone
  • hallucinations
  • sleep apnea
  • a skin rash
  • a condition where the body is unable to maintain adequate blood flow called shock
  • apnea, a breathing interruption
  • trouble breathing
  • a significant type of allergic reaction called anaphylaxis
  • accidental falls
  • an accidental injury

If experienced, these tend to have a Less Severe expression i

  • erythema or redness of skin or mucous membrane
  • hives
  • a skin rash
  • insufficiency of the hypothalamus and pituitary gland
  • agitation
  • an extreme sense of wellbeing called euphoria
  • a migraine headache
  • lazy eye
  • a change in vision
  • ringing in the ears
  • throat irritation
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • a painful, red or swollen tongue
  • urinary tract infection
  • the inability to have an erection
  • increased sensitivity of the skin to the sun
  • dry skin
  • arthritis
  • joint pain
  • difficulty sleeping
  • flu-like symptoms
  • chills
  • visible water retention
  • decreased appetite
  • increased hunger
  • a change in voice
  • heart throbbing or pounding
  • difficulty swallowing
  • gas
  • difficult or painful urination
  • an inability to completely empty the bladder
  • high blood sugar
  • abnormal liver function tests
  • anxious feelings
  • fast heartbeat

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.