What should I Know Regarding Pregnancy, Nursing and Administering TOLTERODINE TARTRATE ER to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • If you are nursing

  • If you are an adult over 60

  • management or monitoring precaution: Urogenital-Highly anticholinergic; pre-existing urinary retention is contraindicated. Neuro/Psych-May predispose to sedation, confusion and falls. High risk of delirium. Gastrointestinal-Risk for worsening or new-onset constipation. Hepatic-Lower doses are recommended in severe impairment. Renal-CrCL=10-30 mL/min. affects drug disposition; lower doses recommended. Cardiovascular-Heart failure, bradyarrhythmias, hypomagnesemia, hypokalemia may increase the risk of QT prolongation.
  • Pediatric use

  • Severe Precaution: Aggression, abnormal and hyperactive behavior reported. Increased risk of urinary tract infections, Efficacy not established.
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.