Who should not take EXCEDRIN MIGRAINE?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:

Conditions:

  • caloric undernutrition
  • acute liver failure
  • liver problems
  • severe renal impairment
  • a condition where the body is unable to maintain adequate blood flow called shock
  • acetaminophen overdose
  • acute inflammation of the liver due to hepatitis C virus
  • high blood pressure
  • heart attack within the last 30 days
  • abnormal heart rhythm
  • an ulcer from too much stomach acid
  • necrotizing enterocolitis, or inflammation and tissue death in the colon and small intestine
  • severe liver disease
  • seizures
  • difficulty sleeping
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 5 (failure)
  • systemic mastocytosis
  • low vitamin K levels
  • a type of joint disorder due to excess uric acid in the blood called gout
  • anemia
  • hemophilia
  • a decrease in the blood clotting protein prothrombin
  • blood clotting disorder - von Willebrand's disease
  • decreased blood platelets
  • alcoholism
  • Reye's syndrome
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • nasal polyp
  • an ulcer from too much stomach acid
  • stomach or intestinal ulcer
  • liver problems
  • bleeding of the stomach or intestines
  • decreased kidney function
  • pregnancy
  • a mother who is producing milk and breastfeeding
  • anemia from pyruvate kinase and G6PD deficiencies
  • overdose of the drug aspirin
  • aspirin exacerbated respiratory disease

Free RX Coupon

Save up to 80% on your prescriptions.

Available coupons

Save up to 80% on your prescription with WebMDRx

Drug Survey

Have you ever purchased Excedrin Migraine?

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.