AVONEX Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • depression
  • headache
  • abnormal liver function tests
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • urinary tract infection
  • muscle pain
  • nausea
  • intense abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • anemia
  • suicidal thoughts
  • widening of blood vessels
  • a common cold
  • itching
  • hives
  • dizziness
  • a skin rash
  • puffy face from water retention
  • wheezing
  • trouble breathing
  • chest pain
  • a hypersensitivity reaction to a drug
  • reactions at the site of the injection

If experienced, these tend to have a Less Severe expression i

  • a migraine headache
  • a change in vision
  • inflammation of the tissue lining the sinuses
  • hair loss
  • joint pain
  • an increased need to urinate often
  • a feeling of general discomfort called malaise

RARE side effects

If experienced, these tend to have a Severe expression i

  • overactive thyroid gland
  • a condition with low thyroid hormone levels
  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • hemolytic uremic syndrome, a condition that affects the kidney and the blood
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • decreased blood platelets
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • mental problems from taking the drug
  • a disorder of the retina of the eye
  • chronic heart failure
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • bronchitis
  • acute liver failure
  • liver inflammation resulting from an abnormal immune response
  • liver damage
  • nephrotic syndrome, a type of kidney disorder
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • systemic lupus erythematosus, an autoimmune disease
  • seizures
  • high amount of bilirubin in the blood
  • swelling of the tongue
  • dead skin
  • a significant type of allergic reaction called anaphylaxis
  • pulmonary arterial hypertension
  • a blood clot in a retinal vein
  • infection at injection site

If experienced, these tend to have a Less Severe expression i

  • abnormally long or heavy periods
  • bleeding not related to menstrual period
  • excessive sweating

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.