Who should not take Capecitabine?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:

Conditions:

  • an infection
  • very serious loss of body water
  • anemia
  • decreased blood platelets
  • low levels of a type of white blood cell called neutrophils
  • coronary artery disease
  • abnormal heart rhythm
  • abnormal EKG with QT changes from birth
  • stomatitis
  • a condition with painful swelling and sores inside the mouth
  • necrotizing enterocolitis
  • or inflammation and tissue death in the colon and small intestine
  • liver problems
  • high amount of bilirubin in the blood
  • erythrodysesthesia or tingling
  • pain
  • redness
  • and edema in the hands and feet
  • excessive diarrhea
  • pregnancy
  • a mother who is producing milk and breastfeeding
  • dihydropyrimidine dehydrogenase deficiency
  • chronic kidney disease stage 3A (moderate)
  • chronic kidney disease stage 3B (moderate)
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 5 (failure)
  • kidney disease with likely reduction in kidney function

Allergies:

  • Pyrimidine Analogues

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.