CAPECITABINE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • anemia
  • decreased blood platelets
  • low levels of a type of white blood cell called neutrophils
  • erythrodysesthesia or tingling, pain, redness, and edema in the hands and feet

If experienced, these tend to have a Less Severe expression i

  • stomatitis, a condition with painful swelling and sores inside the mouth
  • muscle pain
  • low energy
  • decreased appetite
  • nausea
  • vomiting
  • intense abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • blood clot formation in vein
  • blocked bowels with decreased peristaltic movement
  • bleeding of the stomach or intestines
  • chest pain

If experienced, these tend to have a Less Severe expression i

  • mood changes
  • a change in vision
  • pink eye
  • eye irritation
  • a sore throat
  • indigestion
  • constipation
  • increased sensitivity of the skin to the sun
  • erythema or redness of skin or mucous membrane
  • itching
  • a condition with loosening of the nails from the nailbed called onycholysis
  • a nail disorder
  • hair loss
  • skin discoloration
  • joint pain
  • backache
  • dizziness
  • difficulty sleeping
  • taste impairment
  • weight loss
  • headache
  • low energy and weakness
  • upper abdominal pain

RARE side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • dehydration
  • low platelet count and bleeding from immune response
  • a type of brain function problem called encephalopathy
  • leukoencephalopathy, a disease of the white matter of the brain
  • inflammation of the cornea of the eye
  • high blood pressure
  • a heart attack
  • angina, a type of chest pain
  • a low supply of oxygen rich blood to the heart
  • a clot in the lung
  • cardiomyopathy, a disease of the heart muscle
  • abnormal heart rhythm
  • heart failure
  • thrombophlebitis, an inflamed vein due to a blood clot
  • low blood pressure
  • pneumonia
  • an ulcer in the esophagus
  • necrotizing enterocolitis, or inflammation and tissue death in the colon and small intestine
  • blood coming from anus
  • excess liver fibrous tissue
  • liver failure
  • inflammation of the liver called hepatitis
  • kidney failure
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • subacute cutaneous lupus erythematosus
  • high amount of bilirubin in the blood
  • excessive diarrhea
  • a type of allergic reaction called angioedema
  • inflammation of the liver with stoppage of bile flow
  • inflammation of a vein
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • radiation recall syndrome

If experienced, these tend to have a Less Severe expression i

  • cough
  • diarrhea

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.