Estradiol Insert Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • Abnormally Long Or Heavy Periods
  • Bleeding Not Related To Menstrual Period
  • Breast Tenderness

If experienced, these tend to have a Less Severe expression

  • Backache
  • Breast Tenderness
  • Head Pain
  • Infection
  • Stomach Cramps
  • Swelling Of The Abdomen
  • Weight Gain
  • Yeast Infection Of Vagina And Vulva

INFREQUENT side effects


If experienced, these tend to have a Less Severe expression

  • Acne
  • Altered Interest In Having Sexual Intercourse
  • Cramps
  • Discharge From The Vagina
  • Enlarged Breasts
  • Feeling Weak
  • Head Pain
  • Infection Due To The Candida Fungus
  • Inflammation Or Infection Of Vagina
  • Itching
  • Migraine Headache
  • Pelvic Pain
  • Urinary Tract Infection
  • Uterine Cramps

RARE side effects


If experienced, these tend to have a Severe expression

  • Blockage Of Gallbladder
  • Blood Clot
  • Blood Clot In A Deep Vein Of The Extremities
  • Breast Tumor
  • Cancer In The Lining Of The Uterus
  • Cancer Of The Ovary
  • Cancer Of The Uterus
  • Cystic Disease Of The Breast
  • Diarrhea
  • Disorder Of Mental Processes Due To A Brain Disease
  • Enlarged Breasts
  • Erythema Multiforme
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Fluid Secretion From The Breast
  • Giant Hives
  • Heart Attack
  • High Amount Of Calcium In The Blood
  • High Amount Of Triglyceride In The Blood
  • High Blood Pressure
  • Hypersensitivity Drug Reaction
  • Inflammation Of The Gallbladder
  • Life Threatening Allergic Reaction
  • Lung Embolism
  • Obstruction Of A Blood Vessel By A Blood Clot
  • Overgrowth Of The Uterine Lining
  • Pancreatitis
  • Problems With Eyesight
  • Puberty At An Earlier Age Than Would Be Expected
  • Retinal Thrombosis
  • Skin Condition Marked By Red And Painful Nodules
  • Stomach Or Intestine Blockage
  • Stroke
  • Toxic Shock
  • Unspecified Lump In Breast
  • Uterine Fibroid
  • Vaginal Irritation
  • Vaginal Ulcer
  • Weight Gain

If experienced, these tend to have a Less Severe expression

  • Altered Interest In Having Sexual Intercourse
  • Bleeding Not Related To Menstrual Period
  • Chest Pain
  • Chronic Trouble Sleeping
  • Depression
  • Diarrhea
  • Dizzy
  • Fluid Secretion From The Breast
  • Genital Itching
  • High Amount Of Calcium In The Blood
  • High Amount Of Triglyceride In The Blood
  • High Blood Pressure
  • Hives
  • Itching
  • Migraine Headache
  • Mood Changes
  • Ovarian Cyst
  • Painful Periods
  • Stomach Cramps
  • Throwing Up
  • Vaginal Irritation
  • Water Retention
  • Yellow-Brown Patches On Skin

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.