If you are:
Only When Necessary: INSUFFICIENT HUMAN DATA; ANIMAL DATA SUG DEV TOX
Precaution: POTENTIAL FOR ADVERSE EFFECTS IN NURSING INFANT
An adult over 60:
management or monitoring precaution: General-CNS and systemic drug effects may be more severe in the elderly. Renal-Doses should be reduced for CrCL<30mL/min. Incidence of toxic reactions may be higher if CrCL<51 mL/min. Neuro/Psych-Monitor very closely for worsening of or new onset depression.
Giving Pegasys Kit to a child under 12:
management or monitoring precaution: Monitor height and weight for impaired growth. Monitor blood counts.
Contraindication: Contains benzyl alcohol; possible increased incidence of neurologic and respiratory adverse events in neonates and infants. Growth inhibition reported. Contraindicated per manufacturer.
management or monitoring precaution: Delays in growth reported in pediatric studies. Safety and efficacy not established age < 5 years.