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    Nifedipine

    precautions

    What should I know regarding pregnancy, nursing and administering Nifedipine to children or the elderly?

    If you are:

    Pregnant:

    Only When Necessary: TERATOGENIC IN ANIMALS AT AT DOSES 5 TO 50 TIMES MRHD

    Nursing:

    No Known Risk: AMOUNT EXCRETED IS NEGLIGIBLE, ADVERSE EFFECT POTENTIAL FOR INFANT UNKNOWN

    An adult over 60:

    Contraindication: Sustained release products are preferred. Risks for hypotension, edema and constipation. Decreased clearance and higher AUC in the elderly. Generally not recommended.

    management or monitoring precaution: Decreased clearance and higher AUC in the elderly. Risks for hypotension, edema and constipation. Sustained release products are preferred.

    Giving nifedipine to a child under 12:

    Severe Precaution: Use the lowest effective dose; risk of severe hypotension. Caution with CNS injury, risk of stroke, seizure.

    management or monitoring precaution: Extended release dose form may not be appropriate.

    Severe Precaution: No dosing guidelines available age <1 year. Not recommended per manufacturer.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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