Trientine HCL

COMMON BRAND(S): Syprine

GENERIC NAME(S): Trientine

OTHER NAME(S): Trientine Capsule

Uses

Uses

This medication is used to treat a certain inherited disorder (Wilson's disease). This disorder causes too much copper to build up in the liver, brain, and other parts of the body. Trientine works by binding to copper, which helps your body get rid of extra copper. This can decrease symptoms such as problems with speech/swallowing/coordination, tiredness, lack of appetite, abdominal pain, yellowing eyes/skin, fluid buildup in the legs/abdomen, uncontrolled movements, or muscle stiffness.

How to use Trientine HCL

Take this medication by mouth on an empty stomach, at least 1 hour before meals or 2 hours after meals as directed by your doctor, usually 2 to 4 times daily. Take this medication at least 1 hour apart from any other drug, food, or milk. Swallow the capsules whole with water. Do not open or chew the capsules. The dosage is based on your medical condition and response to treatment.

For the best effect, follow a low-copper diet as directed by your doctor and take this medication regularly. To help you remember, take it at the same times each day.

For the first month of treatment, check your temperature every night and tell your doctor of any fever or rash.

If your doctor directs you to also take an iron supplement, take it at least 2 hours before or after trientine.

Tell your doctor if your condition does not get better or if it gets worse.

If you accidentally come in contact with the capsule contents, wash the area promptly with water to avoid an allergic reaction.

Side Effects

Side Effects

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication and a low-copper diet may increase the risk for iron deficiency. Tell your doctor right away if you have symptoms such as feeling very tired, weakness, pale skin, chest pain, fast heartbeat, shortness of breath, cold hands/feet. Your doctor may direct you to take an iron supplement for a short time (see also How to Use section).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Precautions

Before taking trientine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain immune disease (systemic lupus erythematosus).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Children and pregnant or menstruating women may be at greater risk for developing iron deficiency while taking this drug.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Interactions

See also How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

Lab and/or medical tests (such as blood/urine copper levels) should be done while you are taking this medication. Keep all medical and lab appointments.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store in a tightly closed container in the refrigerator away from moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised February 2019. Copyright(c) 2019 First Databank, Inc.

Images
trientine 250 mg capsule
trientine 250 mg capsuleiconicon
trientine 250 mg capsule

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A272
trientine 250 mg capsule
trientine 250 mg capsuleiconicon
trientine 250 mg capsule

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white,light brown
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1203
trientine 250 mg capsule
trientine 250 mg capsuleiconicon
trientine 250 mg capsule

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light brown
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TRN, 250
trientine 250 mg capsule
trientine 250 mg capsuleiconicon
trientine 250 mg capsule

color
light brown
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SYPRINE, ATON 710
trientine 250 mg capsule
trientine 250 mg capsuleiconicon
trientine 250 mg capsule

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caramel
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TRIENTINE, 250 mg
trientine 250 mg capsule
trientine 250 mg capsuleiconicon
trientine 250 mg capsule

color
orange,white
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NAV, 101
trientine 250 mg capsule
trientine 250 mg capsule

color
white
shape
oblong
imprint
A272
This medicine is a white, oblong, capsule imprinted with "A272".
trientine 250 mg capsule
trientine 250 mg capsule

color
white,light brown
shape
oblong
imprint
1203
This medicine is a white light brown, oblong, capsule imprinted with "1203".
trientine 250 mg capsule
trientine 250 mg capsule

color
light brown
shape
oblong
imprint
TRN, 250
This medicine is a light brown, oblong, capsule imprinted with "TRN" and "250".
trientine 250 mg capsule
trientine 250 mg capsule

color
light brown
shape
oblong
imprint
SYPRINE, ATON 710
This medicine is a light brown, oblong, capsule imprinted with "SYPRINE" and "ATON 710".
trientine 250 mg capsule
trientine 250 mg capsule

color
caramel
shape
oblong
imprint
TRIENTINE, 250 mg
This medicine is a caramel, oblong, capsule imprinted with "TRIENTINE" and "250 mg".
trientine 250 mg capsule
trientine 250 mg capsule

color
orange,white
shape
oblong
imprint
NAV, 101
This medicine is a orange white, oblong, capsule imprinted with "NAV" and "101".

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.