DOXORUBICIN HCL Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • inflammation of the esophagus

If experienced, these tend to have a Less Severe expression i

  • hair loss
  • nausea
  • vomiting
  • abnormal color of urine

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • cardiomyopathy, a disease of the heart muscle
  • chronic heart failure
  • fibrous hardening of the walls of the veins
  • stomach or intestinal ulcer
  • redness of skin following radiation therapy
  • reactions at the site of the injection
  • tissue death

If experienced, these tend to have a Less Severe expression i

  • increased sensitivity of the skin to the sun
  • diarrhea

RARE side effects

If experienced, these tend to have a Severe expression i

  • dehydration
  • significantly decreased activity of the bone marrow
  • decreased blood platelets
  • a disorder of the peripheral nerves that enable movement called peripheral motor neuropathy
  • inflammation of the covering of the heart or pericardium
  • abnormal heart electrical signals
  • rapid ventricular heartbeat
  • ventricular premature beats
  • slow heartbeat
  • sinus tachycardia, a type of fast heart rate
  • left ventricular heart failure
  • inflammation of the middle tissue heart muscle
  • toxicity to the heart
  • obstruction of a blood vessel by a blood clot
  • myelodysplastic syndrome, a bone marrow disorder
  • coma
  • seizures
  • erythrodysesthesia or tingling, pain, redness, and edema in the hands and feet
  • trouble breathing
  • a significant type of allergic reaction called anaphylaxis
  • damage to the skin and tissue around the injection site
  • tissue death or necrosis in the intestinal colon
  • therapy-related acute myeloid leukemia
  • radiation recall syndrome
  • a high alanine transaminase level
  • a high aspartate transaminase level
  • tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i

  • inflammation of the cornea of the eye
  • pink eye
  • excessive watery eyes
  • itching
  • discoloration of nail
  • skin discoloration
  • darkening of the skin
  • fever
  • chills
  • decreased appetite
  • weight gain
  • generalized weakness
  • a feeling of general discomfort called malaise
  • intense abdominal pain
  • hyperpigmentation of the inside of the mouth
  • drug-induced hot flashes
  • peripheral sensory nerve disorder

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.