EZETIMIBE-SIMVASTATIN Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • muscle pain
  • atrial fibrillation
  • bronchitis
  • muscle problems related to the drug and having the SLCO1B1 gene

If experienced, these tend to have a Less Severe expression i

  • a common cold
  • indigestion
  • constipation
  • dizziness
  • a skin rash
  • headache
  • nausea
  • heartburn
  • diarrhea
  • intense abdominal pain
  • gas

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • atrial fibrillation
  • a common cold
  • gallstones
  • inflammation of the tissue lining the sinuses
  • urinary tract infection
  • muscle pain

If experienced, these tend to have a Less Severe expression i

  • inflammation of the tissue lining the sinuses
  • a type of stomach irritation called gastritis
  • a type of skin condition with redness and itching called eczema
  • joint pain
  • backache
  • low energy
  • flu-like symptoms
  • heart throbbing or pounding
  • gas
  • throat irritation
  • the flu
  • muscle pain
  • pain in the arms or legs
  • diarrhea
  • stomach cramps
  • difficulty sleeping
  • visible water retention

RARE side effects

If experienced, these tend to have a Severe expression i

  • diabetes
  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • anemia
  • large purple or brown skin blotches
  • decreased blood platelets
  • increased eosinophils in the blood
  • a disease with shrinking and weaker muscles called myopathy
  • clouding of the lens of the eye called cataracts
  • inflammation of the blood vessels
  • bronchitis
  • liver tissue death
  • liver failure
  • inflammation of the liver called hepatitis
  • a blockage of the bile duct that resulting in high bilirubin levels
  • urinary tract infection
  • inflammation of the skin with blisters
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • hives
  • a condition with symptoms that resemble lupus
  • inflammation of the skin and muscle
  • muscle pain and stiffness in the shoulder, neck and pelvis
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • muscle inflammation
  • trouble breathing
  • chest pain
  • abnormal liver function tests
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • chronic inflammation of muscles in the body called polymyositis
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • lung tissue problem
  • pancreatitis
  • paralysis of some or all of the muscles of the eye
  • immune-mediated necrotizing myopathy
  • inflammation of the gallbladder
  • acute inflammation of the pancreas
  • a skin rash
  • a hypersensitivity reaction to a drug
  • low levels of white blood cells
  • arthritis
  • increased gamma-glutamyl transferase

If experienced, these tend to have a Less Severe expression i

  • confusion
  • altered interest in having sexual intercourse
  • depression
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • blurred vision
  • a stuffy and runny nose
  • dry mouth
  • the inability to have an erection
  • enlarged breasts
  • increased sensitivity of the skin to the sun
  • itching
  • hair loss
  • dry skin
  • skin discoloration
  • muscle spasm
  • muscle weakness
  • cramps
  • memory loss
  • sensation of spinning or whirling
  • difficulty sleeping
  • fever
  • muscle tremors
  • taste impairment
  • numbness
  • skin nodules
  • visible water retention
  • temporary redness of face and neck
  • decreased appetite
  • cough
  • vomiting
  • difficult or painful urination
  • an increased need to urinate often
  • urination during the night
  • high blood sugar
  • a feeling of pins and needles on skin
  • abnormal sensations of the skin
  • a feeling of general discomfort called malaise
  • paralysis of nerves for the face
  • anxious feelings
  • dizziness
  • nausea
  • indigestion
  • joint pain
  • generalized weakness

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.