If you are:
Only When Necessary: REPORTS OF ARTHROPATHY WITH QUINOLONES IN ANIMAL STUDIES;CONSIDER RISK/BENEFIT
Precaution: CONSIDER RISK/BENEFIT PER MFR;ARTHROPATHY & OSTEOCHONDROSIS IN ANIMAL STUDIES
An adult over 60:
management or monitoring precaution: Musculoskeletal-Risk for tendon rupture increases with aging. Increased risk with steroid use. Cardiovascular-Elderly at increased risk for QT prolongation. Neuro/Psych-Risk for peripheral neuropathy which may affect walking and increase fall risk.
Giving Factive to a child under 12:
Severe Precaution: No safety and efficacy age < 18 years. Tendinitis risk. Arthropathy seen in animal studies.