TRUVADA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

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    If experienced, these tend to have a Less Severe expression i

    • depression
    • dizziness
    • difficulty sleeping
    • low energy
    • a skin rash
    • headache
    • nausea
    • diarrhea
    • abnormal dreams
    • abnormal fat distribution associated with HIV

    INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

    • low amount of phosphate in the blood
    • Fanconi syndrome, a condition of the kidneys resulting in excessive urination, thirst and vomiting
    • decreased kidney function
    • trouble breathing

    If experienced, these tend to have a Less Severe expression i

    • throat irritation
    • inflammation of the tissue lining the sinuses
    • inflammation of the skin with blisters
    • itching
    • hives
    • weight loss
    • vomiting
    • generalized weakness
    • intense abdominal pain
    • a type of bumpy skin rash called a maculopapular rash
    • anxious feelings

    RARE side effects

    If experienced, these tend to have a Severe expression i

    • osteomalacia, or softening of bones
    • increased blood acidity due to high levels of lactic acid
    • low amount of potassium in the blood
    • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
    • Guillain-Barre syndrome
    • pneumonia
    • liver inflammation resulting from an abnormal immune response
    • enlarged fatty liver
    • damage to the liver and inflammation
    • a type of kidney inflammation called interstitial nephritis
    • acute kidney failure
    • renal tubular necrosis, a kidney disorder
    • kidney failure
    • a condition with muscle tissue breakdown called rhabdomyolysis
    • decreased calcification or density of bone
    • abnormal liver function tests
    • a type of allergic reaction called angioedema
    • a feeling of pins and needles on skin
    • chronic inflammation of muscles in the body called polymyositis
    • pancreatitis
    • a condition that results in overproduction of thyroid hormones called Graves' disease
    • a high alanine transaminase level
    • a high aspartate transaminase level

    If experienced, these tend to have a Less Severe expression i

    • a disease with shrinking and weaker muscles called myopathy
    • a stuffy and runny nose
    • indigestion
    • skin discoloration
    • backache
    • muscle weakness
    • muscle pain
    • fever
    • excessive sweating
    • pain
    • cough

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.