TYSABRI Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • depression
  • urinary tract infection
  • a skin rash

If experienced, these tend to have a Less Severe expression i

  • a common cold
  • a lower respiratory infection
  • inflammation of the lining of the stomach and intestines
  • inflammation or infection of the vagina
  • joint pain
  • low energy
  • pain
  • headache
  • nausea
  • diarrhea
  • intense abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • damage to the liver and inflammation
  • inflammation of the skin due to an allergy
  • hives
  • fluid retention in the legs, feet, arms or hands

If experienced, these tend to have a Less Severe expression i

  • pain with menstruation
  • itching
  • backache
  • dizziness
  • cough
  • an increased need to urinate often

RARE side effects

If experienced, these tend to have a Severe expression i

  • mycobacterium avium bacteria infection
  • herpes simplex encephalitis
  • opportunistic fungal infection
  • pneumonia with a fungus called Pneumocystis jirovecii
  • an infection
  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • decreased blood platelets
  • suicidal thoughts
  • leukoencephalopathy, a disease of the white matter of the brain
  • high blood pressure
  • inflammation of the tonsils
  • the flu
  • appendicitis
  • acute liver failure
  • liver damage
  • gallstones
  • an ovarian cyst
  • high amount of bilirubin in the blood
  • trouble breathing
  • chest tightness
  • abnormal liver function tests
  • a significant type of allergic reaction called anaphylaxis
  • a hypersensitivity reaction to a drug
  • progressive multifocal leukoencephalopathy, a type of brain infection
  • encephalitis due to varicella zoster virus
  • meningitis due to varicella zoster virus
  • herpes simplex meningitis
  • acute retinal necrosis

If experienced, these tend to have a Less Severe expression i

  • a herpes simplex infection
  • absence of menstrual periods
  • muscle pain
  • drowsiness
  • fainting
  • chills
  • muscle tremors
  • weight gain
  • weight loss
  • anxious feelings

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.