What should I Know Regarding Pregnancy, Nursing and Administering Ibuprofen-oxycodone Oral to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • Not Recommended:
  • If you are nursing

  • Precaution: MONITOR FOR CHANGES IN RESPIRATION, GI EFFECTS, SEDATION, FEEDING PATTERN
  • Precaution: LOW LEVELS IN BREAST MILK, WITH NO KNOWN RESULTING ADVERSE EFFECT ON INFANT
  • If you are an adult over 60

  • management or monitoring precaution: General-Consider adding naloxone Rx. Pulmonary-Life threatening respiratory depression risk with high doses, cachexia, or debilitation due to altered pharmacokinetics (poor fat stores, muscle wasting, or altered clearance). Monitor closely at initiation and dose titration. Neuro/Psych-Risk for increased confusion and delirium. May increase fall risk. Avoid treatment with 3 or more CNS active drugs. Gastrointestinal-Constipation risk. Urogenital-Urinary retention risk.
  • management or monitoring precaution: Gastrointestinal-Risk for ulceration or serious GI bleed; highest with history of PUD or GI bleed. Renal-Risk for exacerbation of CKD. Cardiovascular-May exacerbate pre-existing hypertension or CHF. Risk of cardiovascular thrombotic events, including MI and stroke. This risk may occur early in treatment and increases with duration of use. Risk for reinfarction with minimal NSAID use post-MI. Contraindicated with CABG. Hepatic-Elevated hepatic transaminases may occur with chronic use.
  • Pediatric use

  • Severe Precaution: Risk of respiratory and CNS depression. No safety and efficacy. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
  • Severe Precaution: Potential increased sensitivity to effects, adverse CNS effects and respiratory depression. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
  • Severe Precaution: Safety and efficacy for children less than 6 months not established.
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.