What should I Know Regarding Pregnancy, Nursing and Administering Acyclovir to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • If you are nursing

  • If you are an adult over 60

  • management or monitoring precaution: Renal-Dose interval adjustment necessary for CrCL<25 mL/min. for high dose (800 mg oral) treatment. For IV therapy: CrCL >25-50 mL/min, adjust interval to 12 hours; CrCL>10-25mL/min, adjust interval to 24 hours; CrCL<11mL/min, decrease dose by half and use a 24 hour interval. Renal toxicity more common in the elderly. Neuro/Psych-Dizziness, somnolence, hallucinations, confusion and coma are reported more commonly in the elderly.
  • Pediatric use

  • Severe Precaution: IV route preferred. Safety and efficacy of oral route not established age < 2 years. Rare use for immunocompromised patients in treating zoster or varicella.
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.