Who should not take Phenytoin Sodium Intravenous?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • diabetes
  • osteomalacia, or softening of bones
  • low amount of albumin proteins in the blood
  • porphyria
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of granulocytes, a type of white blood cell
  • alcoholism
  • alcohol intoxication
  • myasthenia gravis, a skeletal muscle disorder
  • a heart attack
  • complete heart block
  • second degree atrioventricular heart block
  • Adams-Stokes syndrome
  • sinus bradycardia
  • abnormal heart rhythm
  • sudden and serious symptoms of heart failure called acute decompensated heart failure
  • low blood pressure
  • decreased lung function
  • overgrowth of gums onto teeth
  • liver problems
  • decreased kidney function
  • systemic lupus erythematosus, an autoimmune disease
  • decreased calcification or density of bone
  • a body temperature higher than 101 degrees Fahrenheit
  • swollen lymph nodes
  • pregnancy
  • CYP2C9 poor metabolizer
  • HLA-B *15:02 positive gene status

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.