This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Initially, both medicines can cause sedation or suppress your natural urge to breathe. Over time, the phenobarbital may speed up how quickly your liver processes your pain medicine.
What might happen:
Initially, you could have more side effects from both medicines, but after you have been on the combination for a while your pain medicine may not work as well.
What you should do about this interaction:
Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to monitor you more closely to be sure that you are not having side effects and that both medications are working. Your medicine doses may need to be adjusted.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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