Who should not take DEFERASIROX?
The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:
- cancer or malignancy
- a significant decrease in certain blood clotting cells called platelets
- low levels of a type of white blood cell called neutrophils
- increased pressure in the eye
- clouding of the lens of the eye called cataracts
- hearing loss
- stomach or intestinal ulcer
- hardening of the liver
- liver problems
- bleeding of the stomach or intestines
- acute kidney failure
- myelodysplastic syndrome, a bone marrow disorder
- high amount of bilirubin in the blood
- elevation of proteins in the urine
- abnormal liver function tests
- a patient who is producing milk and breastfeeding
- multiple organ failure
- chronic kidney disease stage 3A (moderate)
- chronic kidney disease stage 3B (moderate)
- chronic kidney disease stage 4 (severe)
- chronic kidney disease stage 5 (failure)
- kidney disease with likely reduction in kidney function
- Child-Pugh class B liver impairment
- Child-Pugh class C liver impairment
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.