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    Deferasirox Tablet, Dispersible

    precautions

    What should I know regarding pregnancy, nursing and administering Deferasirox Tablet, Dispersible to children or the elderly?

    If you are:

    Pregnant:

    Not Recommended: INSUFF HUMAN DATA;ANIMAL DATA SUGG DEVELOPMENTAL TOXICITY AT 0.2--1 X MRHD

    Nursing:

    Absolute Contraindication: DRUG EXCRETED IN RAT STUDIES, POTENTIAL FOR IRON DEPLETION IN INFANT.

    An adult over 60:

    management or monitoring precaution: General-Elderly have increased risk for adverse effects. Renal-Contraindicated with CrCL<40mL/min. Reduce dose by 50% for CrCL=40-60 mL/min. Hepatic-Risk for worsened hepatic impairment and failure. Monitor LFTs closely. Gastrointestinal-GI bleed risk. Hematologic-Caution in high risk myelodysplastic syndromes due to increased incidence of toxicities.

    Giving deferasirox Tablet, Dispersible to a child under 12:

    management or monitoring precaution: No safety and efficacy established age < 2 years.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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