Who should not take SUNITINIB MALATE?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • overactive thyroid gland
  • a condition with low thyroid hormone levels
  • diabetes
  • low blood sugar
  • decreased function of the adrenal gland
  • low amount of magnesium in the blood
  • high amount of magnesium in the blood
  • high levels of potassium in the blood
  • low amount of potassium in the blood
  • hemolytic uremic syndrome, a condition that affects the kidney and the blood
  • anemia
  • decreased blood platelets
  • significant uncontrolled high blood pressure
  • a heart attack
  • a low supply of oxygen rich blood to the heart
  • cardiomyopathy, a disease of the heart muscle
  • torsades de pointes, a type of abnormal heart rhythm
  • slow heartbeat
  • prolonged QT interval on EKG
  • left ventricular heart failure
  • heart failure
  • sudden and serious symptoms of heart failure called acute decompensated heart failure
  • abnormal EKG with QT changes from birth
  • a localized weakening and ballooning in an artery wall called an arterial aneurysm
  • obstruction of a blood vessel by a blood clot
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • bleeding
  • liver failure
  • damage to the liver and inflammation
  • liver problems
  • severe liver disease
  • nephrotic syndrome, a type of kidney disorder
  • recent operation
  • seizures
  • high amount of bilirubin in the blood
  • coughing up of blood
  • elevation of proteins in the urine
  • abnormal liver function tests
  • pregnancy
  • a mother who is producing milk and breastfeeding
  • pancreatitis
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • dissection of artery
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.