SUNITINIB MALATE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • an increased risk of bleeding
  • high blood pressure
  • chronic heart failure
  • bleeding
  • abnormal liver function tests
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • indigestion
  • constipation
  • dry skin
  • skin discoloration
  • joint pain
  • backache
  • pain in the arms or legs
  • dizziness
  • low energy
  • taste impairment
  • a skin rash
  • fluid retention in the legs, feet, arms or hands
  • decreased appetite
  • headache
  • cough
  • nausea
  • vomiting
  • gas
  • diarrhea
  • generalized weakness
  • intense abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • low blood sugar
  • an increased sodium level in the blood
  • dehydration
  • low amount of potassium in the blood
  • decreased blood platelets
  • low levels of a type of white blood cell called neutrophils
  • a decreased number of lymphocytes in the blood
  • high amount of bilirubin in the blood
  • tumor bleeding

If experienced, these tend to have a Less Severe expression i

  • a sore tongue
  • hair loss
  • muscle pain

RARE side effects

If experienced, these tend to have a Severe expression i

  • thyroid gland inflammation
  • low amount of phosphate in the blood
  • anemia
  • a disease with shrinking and weaker muscles called myopathy
  • a heart attack
  • a low supply of oxygen rich blood to the heart
  • a clot in the lung
  • cardiomyopathy, a disease of the heart muscle
  • torsades de pointes, a type of abnormal heart rhythm
  • prolonged QT interval on EKG
  • left ventricular heart failure
  • acute cerebral infarction
  • a transient ischemic attack, a type of stroke that lasts only a few minutes
  • a stroke
  • a localized weakening and ballooning in an artery wall called an arterial aneurysm
  • obstruction of a blood vessel by a blood clot
  • a blood clot in an artery
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • escape of fluid into the lungs
  • inflammation of the esophagus
  • liver failure
  • inflammation of the liver called hepatitis
  • inflammation of the gallbladder
  • nephrotic syndrome, a type of kidney disorder
  • kidney failure
  • decreased kidney function
  • pyoderma gangrenosum, a condition where large painful skin sores form
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • erythrodysesthesia or tingling, pain, redness, and edema in the hands and feet
  • impaired wound healing
  • a type of allergic reaction called angioedema
  • a rupture in the wall of the stomach or intestine
  • portions of the jaw bone to die from lack of blood circulation
  • pancreatitis
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • dissection of the aorta
  • a fistula between two body organs
  • necrotizing fasciitis
  • dissection of artery
  • tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i

  • a hormone disorder where the body produces high levels of cortisol called Cushing's syndrome
  • hair discoloration
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.