User Reviews for Motegrity oral

I have type 1 diabetes with gastroparesis which causes chronic constipation. I have tried many medications with no success. Cramping, nausea, bloating, Fullness and the frustrating feeling of feeling like you have to go and not able to. I was having to drink milk of magnesia constantly to help me go. Motegeity has been a savor. I’m not perfect but so much better. The bloating is at a minimum the nausea is pretty much gone as well. I can go most days now. Still a bit of a struggle some days but still production! Key notes: I always take at night. Never eat after. The headaches subsided after about two and a half weeks. But I had to take half a pill ( which is 1 mg) for a month. I have now been on this medication a year. I won’t look back, tip for those whose insurance won’t cover it. Mine wouldn’t because it’s not fda approved for gastroparesis. Takeda help at hand is the program through the manufacturer to get it free for a year if you qualify. I just renewed my second year with them. The only other medicine I take now is IB Guard to help calm my stomach when it’s upset. Good luck to those trying it!! Read More Read Less

Im 34yrs old type 1 diabetic and took motegrity 2mg for my gastroparesis and bloating..it worked very good for about 5 weeks and i was feeling better but unfortunately it stopped working after 5 weeks of use..im again bloated and feeling awful again..

OMG, the headache!!! I've been taking Motegrity 2mg/day for about a week. The only way I could get it to work was to use a suppository about an hour after I took it. However, the crushing headache that comes with this medication is not worth it. I've been suffering all day and no amount of Tylenol will make it go away. And the cost is ridiculous. Cost me $170.00 for thirty pills with a discount card. I will NOT be taking the medication again.

Two weeks on Motegrity, after Linzess stopped working for me. No need for any stimulant laxative, where I needed a liquid glycerin suppository and/or mag citrate weekly, before. I have taken a couple of doses of Miralax when stools tended toward smaller and harder. Overall, I'm delighted. Motegrity is a unique product, and I fervently hope it continues to work for me (and remain available).

I have had chronic constipation for almost 2 years. I was hoping this medication would be an answer. It made me poop after the first pill...then it never worked again. I have been very dizzy after taking this for a few days. I assume the motegrity caused it. Bisacodyl is the only thing that will work for me.

Since this is a form of bowel stimulant medication...I had high hopes it would get me moving. It did not. I took it for several weeks...at different doses. Occasionally, it made my bowels noisy, but nothing meaningful ever happened. My CIC continues...

I have tried Trulance & Linzess which gave me no relief & cost me a fortune. My Dr gave me samples of Motegrity & have had 4 BM's in 3 days. I have had no side effects that would cause me to stop taking this drug. This is amazing & I contacted my Dr to cancel my 2nd Sitz Marker Study MRI pelvis with defecography. I hope this continues to work & that my Ins will cover it to make it affordable.

Honestly, this med has been a big disappointment. I thought it would work for my lack of motility, and chronic constipation. The only effect after 3 weeks of daily use...is some rumbling in my gut. The first two weeks I took 1mg daily...then I upped it to 2mg daily. I have had no BM's as a result.

Was on it for a 9 days. Severe bloating that prevents normal motility. Horrible gas, headaches, dry mouth. Nothing good about this stuff.

Absolutely no effectiveness at all for my colonic inertia.

This should not be given to people with a history of chronic migraines. One dose and with in an hour I had one of the most severe migraines I have ever had. My pain is at a 10 and none of my rescue medications is working to combat this. I will have to ride it out until this is out of my system. I will never take this medication again.

Started taking motegrity about one week ago and it has not been effective.

Finally a medication that works. So far no side effects. I have tried every medication out there and this hands down is the BEST.

Severe headaches days after taking first pill. Terrible cramping, fatigue, chills. Never again will I take take this pill. I'll stick with my linzess.

Coming from someone who has tried so many different medications (Linzess, Amitiza, etc) this one WORKS. It takes about a week or two to get used to but once you figure out how your bowels react to it, it’s life changing. I experienced a little bit of cramping but it really makes you go regularly. No straining either. Definitely give it a shot!! I didn’t experience headaches like some others have said. This has been amazing.

I started using this medication less than a month ago. Although it did work, I experienced every single side affect that is on the list. I am going to continue it to see how I feel in a few weeks. I have been hospitalized several times because of constipation and how bad it gets and NOTHING works for me. I am hoping that the side affects calm down a little bit so I can continue.

I'm a 50 year old woman that has suffered from IBS-C all my life. Recently I started taking daily Miralax (1T) and started a probiotic. Though this helped my have more frequent BM's 4-5/wk, it did nothing to help my frequent IBS pain (left lower abdomen & sever bloating). My GI doctor wanted me to try Motegrity, but honestly the "potential" side effects scared me and some of the reviews. After getting past this apprehension, I started taking 1/2 of a 2mg tablet at bedtime (as one reviewer said she had done). It's been 3.5 wks since starting the medication and I only had a ibs pain/bloat episode the first 2 days of taking the medication, which hardly had time to be effective in 2 days. Since then, no ibs pain and a daily BM (not diarrhea either). I'm so very happy I tried this medication!!! I've had no side effects either. After using all my samples, now my insurance company does not want to cover a perscription and wants me to try Linzess first prior to approval. I've tried that medication in the past without success. I'm so frustrated that now that I've found my "miracle gi pill" I may no be able to continue due to my insurance company. Read More Read Less

This drug works very well - complete and easy bms. The problem is it causes CRUSHING and SEVERE suicidal ideation. Like the most suffocating depression you can imagine. So - use with caution, especially if you have a history of mental illness or have reacted badly to SSRIs in the past. It is no joke. In my opinion you should let someone you trust know you are starting this drug because it is that serious.

I struggled with constipation all my life. After normal bowels for over a year after having my daughter I had a particularly bad time with severe nausea bloating, gas and you guessed it! Constipation. It seemed my good luck was running out and the constipation seemed to be steadily increasing. After taking the 2mg trial - it made the bloating and distention worse. Also the nausea and headache is pretty brutal. Tbh, it only worked for 3 days but each day that has progressed I went less and less. I hate meds that make you dependent on taking them, hate even more that it made my constipation worse. At this rate it's been maybe a week since my last official bowel movement and I had to take laxatives, do yoga for digestive help, and was conscious of having a balanced diet. Its like my intestines seem to have stalled out after taking this, the "mobility"/parastalsis doesnt happen without it and my stomach just doesn't know how to work normally anymore. I'm very sad about this. Skip it. Read More Read Less

I originally started taking this in 2012 when I was experiencing severe smelly gas and constipation. It worked beautifully for helping me have complete, well-formed bowel movements. I no longer need it consistently as I rely on more gentle, natural treatments. But sometimes my system gets really thrown off and motegrity comes to the rescue to get me back on track. The first night whenever I go back to taking it I get a headache and insomnia. It only lasts one night and the benefits feel worth it. Read More Read Less