User Reviews for Methotrexate (Anti-Rheumatic) oral

I have psoriatic arthritis but have not been treated with methotrexate, so this review might get deleted. I do have a comment, though: I urge anyone with inflammatory arthritis to investigate food sensitivities and the "LEAP" protocol. It has greatly improved my arthritis symptoms.

My mum began with 7.5mg/week. After a few days, she hardly eat, her hand shaking most of the time, extremly tired. Three days after the second dose, she had to go hospital in emergency status.

Taken in conjunction with Enbrel, MTX has been terrific. No impairing side effects, although my balance is a bit off.

changes in my gait causing calluses on the sides and bottom of my feet, shedding of my skin on my legs, feet,face and hands; knodules, knots and bumps on my nailbeds, bottom of my feet, sores on my tongue (4-5) days after dosage, chills, fever sneezing, coughing,diarrhea, unexpected and lengthly urination, area around nailbeds on all fingers appear to become numb and peel, ring fingers on both hands continue to split with a black vertical line, right side of fingernails disappear and the fleshly part of the finger become hard as nails and have to be filed with emery boards to foster circulation back into the area for feeling to return and real nail growth begins,; diarrhea, fever, sneezing, coughing, chills lasts 4-5 days after dosageRead More Read Less

When I take this medicine in tablets or injection, I experienced nausea, vomiting etc. I am not interested to use it but it is necessary for me to take injection of 25 mg once a week as advised by the doctor.

I wish so much that I could have been treated immediately for RA with Methotrixate but I could not get in to see the RA specialist in a timely manner. It is very effective. I developed RA after having a knee replacement and I believe that the replacement was a trigger for my immune system. I did have hair loss and now it is growing back even though I am still on methotrixate. I do not have other side effects but may be developing mouth sores. Now I have excellent medical care and am on Medicare.Read More Read Less

Diagnosed with Graves Disease, PA with psoriasis,Sjogrens with Lupus recently added. Went on this drug with hydroxychloroquine (Plaquinil) generic. Within 2 weeks had arthritic knot severely distorting a toenail and pain with every step. Quit the hydroxy but stayed on methotrexate to heal my hands. Months later I learned the met prevented antibiotics from working on an infection and could have an adverse effect on tendons, explaining other pain. That was 2 years ago. I recently had distorted nail removed and don't plan to resume taking either arthritis medication. After enduring a battery of tests, I couldn't see more than 2 areas on x-rays that showed arthritis burls, one looks like a candy corn wedge in my thumb. Now, when I feel a painful lump rising, I rub as hard as I can, as often as possible and it goes away. Somehow, I suspect the solution lies in reducing the inflammation. Think I'll check with mother nature and see what's available that won't poison me.Read More Read Less

I have no reaction to this drug. I have not lost or gained weight. I have not lost any of my hair. I have been nauseated a few times and stomach burning if I don't take the medication with milk or food.

Overall MTX has worked very well for me. Been on it for almost 10 years and no bad side effects or anything else. Feel great, good energy with no flare-ups like when i was taking plaquenil. very satisfied, and will continue taking due to excess effects of not taking it.

Makes me terrible sick, cannot eat, gas, cannot keep anything in stomach. We are going to try another medicnine to see how that does. I have been living on jello, crackers, broth. Getting dehydrated. Bad

The pill is killing me the shot is great no stomach pain

Getting ready to increase taking 4 also, taking humira, methotrexate, prednisone. Also tried plaq, sulfaalzine side effects on both had to be taking off waiting for relief. Have hair loss

This medication was for my psoriasis and the red flacky patches have not cleared up at all.It was also for my severe feet pain with my psoriatic arthritis and that has not helped.

Taking a very small dose (2.5 mg). I've taken it for three weeks and have come down with a very bad rash on both my legs above the ankle and into the foot. I'm not sure it is from this medication but I have not done anything else different. I read that a rash is a bad allergic response. Can't call the doctor as it's Memorial Day weekend and HATE to go to the emergency room. Has anyone ever had a rash from this drug? Thanks.

I took methotrexate pills but they upset my stomach. I switched to injectable methotrexate and have used for about 6 years. It has worked well for me. I also take Naproxen. Sometime I have intestinal discomfort, but GI doctors says there are no apparent problems. I have gradually increased methotrexate dosage over the years to keep RA symptoms at bay. Currently at .8 cc. Seems like it takes a long time to get over a cold when taking methotrexate, so I sometimes stop taking it for a couple of weeks when I'm sick.Read More Read Less

I have been on methotrexate for 9 years! I rarely have any flare-ups and can't believe how well it has worked for me. I hope it continues. Sometimes feel a little nauseous when I take the pills but reduced to 7 pills from 8, once a week and this has helped. (Take 4 in the morning after breakfast and 3 after dinner). So far, so good!

Although I really felt a difference in the month that I took this med (w/plaquenil) the HAIR loss was too much for me! So now I'm going to try sulfasalazine...

I was diagnosed with Scleroderma (CREST) 4 years ago. My rheumatologist wanted me to start methotrexate last spring after the first two months I stopped taking it on my own because I didn't like the side effects. However, after the summer had passed I told my rheumatologist that I had stopped and he pretty much begged to try again so I have been on it for the past three months, I feel weak the day after and have had an increased amount of fatigue. I take folic acid to help with mouth soars and it has helped. Overall, I cannot say that this medicine doesn't help at all but I am still trying to decide whether the side effects are worth staying on the drug. I am young and just starting off my professional career and the methotrexate isn't helping in the work department, there are times I cant work because of the side effects (i.e. fatigue, nausea, stomach pain)Read More Read Less

Took 6 months to take effect but Ive been in remission for about 18 months. Personally, it's been a wonder drug. Give it time before you decide on a biologic. 25mg once a week.

it has lots of unpleasant side effects but I will take them gladly mtx makes my ra tolerable, I take mtx, humira, prednisone and pain med this is the best med combo so far, if I could stay on mtx same dosage and dr not holding it because of bad labs I think my quality of life would improve more but its not always an option since labs are a factor and mtx causing low numbers Nd blood transfusions