Skip to content

    Read user comments about the side effects, benefits, and effectiveness of methotrexate sodium injection.

    Overall User Ratings

    36 Total User Reviews

    User Reviews

    1-5 of 18 Next»
    Condition: Rheumatoid Arthritis
    11/12/2016 9:23:28 AM

    Reviewer: Gaby, 65-74 on Treatment for 6 months to less than 1 year (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    It took around 7 weeks of shots until it began to work. Now I look forward to it as towards the end of the week I am really getting swollen. I also take Palqnil and Sulphasalazine. I use Rogaine for hair loss, which started before Methotrexate. It works great. You just have to use it every night. Also I take Biotin and use Biotin shampoo. I do miss my wine...

    Condition: Rheumatoid Arthritis
    7/17/2014 7:45:33 PM

    Reviewer: Glass Half Full, 35-44 Female on Treatment for 10 years or more (Patient)

    Effectiveness

    Current Rating: 4

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 3

    Comment:
    Love/hate relationship with methotrexate. I'm sure others can relate. Im on injectable mtx, (1ml) which is much easier on my stomach than the pills were. The medicine works and I have taken with and without a biologic combo. It is not a cure all, but it gives me a dramatic reduction in symptoms. Of course, I love that part. The hate part... side effects. The days after my weekly injection, I f ... Show Full Comment

    Condition: Rheumatoid Arthritis
    3/29/2014 4:58:53 AM

    Reviewer: shellymae3, 35-44 Female on Treatment for 10 years or more (Patient)

    Effectiveness

    Current Rating: 4

    Ease of Use

    Current Rating: 3

    Satisfaction

    Current Rating: 1

    Comment:
    I've been taking 1ml sq weekly w/Enbrel (tried Remicade, Arava, Humira, Actemra always go back to Enbrel) for around 13 yrs., first in pill form then switched to injectable in 2006. According to my Dr., the injectable is "absorbed" 20% better than pill(my RA has been pretty severe most of the 14 yrs. I've had it). It does help me somewhat, but I'm starting to feel some side e ... Show Full Comment

    Condition: Rheumatoid Arthritis
    1/23/2014 3:57:54 PM

    Reviewer: Ahyde, 55-64 Female on Treatment for 2 to less than 5 years (Patient)

    Effectiveness

    Current Rating: 2

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 2

    Comment:
    Within an hour of the injection I feel weak and nausea. The next day I am bedridden with severe abdominal pain and my nausea is worse. I quit taking methotrexate once and I felt great. My doctor advised me to stay on this drug since I can't take meds for inflammation.

    Condition: Rheumatoid Arthritis
    6/29/2013 4:26:26 PM

    Reviewer: damselhawk, 55-64 Female on Treatment for 1 to 6 months (Patient)

    Effectiveness

    Current Rating: 1

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    have only been on med for 5 weeks.

    1-5 of 18 Next»

    Ask the pharmacist

    Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
    See the Ask the Pharmacist event schedule.

    Ask a Question

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    bald woman smelling flowers
    Complementary therapies to ease symptoms.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes highlighted
    4 early warning signs.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    sticky notes on face
    10 tips to clear your brain fog.
    Close up of eye
    12 reasons you're distracted.
    Trainer demonstrating exercise for RA
    Exercises for your joints.
    Senior woman using diabetes test kit
    Each one takes 10 minutes or less.
    woman having a good day
    Revitalize your life.

    WebMD the app

    Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

    Find Out More
    IMPORTANT: About This Section and Other User-Generated Content on WebMD

    The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

    Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.