User Reviews for duloxetine oral

I only made it 3 days on this one before I stopped. Just didn't work well with me side effect wise. I will say I felt a difference. My thoughts were still crazy but the emotions behind them were gone so that was a big help Since the first time taking it within 2 hours, and it (never went away) I was nauseated, uneasy, and stomach was messed up. I kept taking them but it just never stopped. On day 3 I was experiencing hot flashes and chills in top of it all and then my legs started hurting so bad where I had to continuously move them for relief. I couldn't make it through. Body just didn't do well with it. Read More Read Less

Here is my experience with one dose of 30 mg Dulexetine DR: Me: Take single pill in morning. Dulexetine: Hey, bro, heard you have anxiety? Me: Yeah, sadly I do. Dulexetine: Don't worry. I'll help. Me: Really. Dulexetine: Yeah. Hehehe. Me: Umm, what's the laughter for. Dulexetine: Oh...just wait... Me: Waits an hour. Dulexetine: Brings down an immediate torrent of badness. Severed anxiety, nausea, diarrhea, dizziness. Me: Oh, god, what are you doing? Dulexetine: Hehehe, your doctor told you to take me, right? Me: ...yeah? Dulexetine: Just hang in there. It will be alright. Me: *Experiences 5 hours of pure hell.* Dulexetine: I've got some more for you. Me: Oh, oh, gods, please...be something nice. Dulexetine: Lulz *Destroys appetite alongside endless waves of nausea and severe universal discomfort.* Me: Gaaahhh! Dulexetine: And, guess what? Me: Shaking in anxiety and crying..."What?" Dulexetine: I'm delayed release. I'll be doing this all night, in continuous waves...hour after hour after hour. Sweet Dreams. Me: Loses ability to sleep. Suffering unlike I have ever personally suffered before. Like seriously, COVID gave me a 104 fever, and that was more fun than this. Dulexetine: *The next day.* Hey, buddy, how do you feel. Me: I hate you! Dulexetine: It's time to take me again! Me: ...um, exactly, 100%, no. Never! *Time passes* Dulexetine: How do you feel now. Me: Good, now that you're leaving my system you toxic jerk. Dulexetine: But...I did my job, didn't I? Me: Umm, what do you mean? Dulexetine: All those other things you were anxious about...they don't seem so bad do they...next to me? Me: Oh, yeah, is...is that how you work? OMG! Dulexetine: Yes. Read More Read Less

After about a month, a noticeable improvement in my balance and a reduction in the tingling sensation & heavy foot feeling. On month three and hoping an increase in dosage may further improve my condition. DMC

I only took one and I feel as I were outside my body I cave eat and I’m confused

My first day taking this I had the worst side effects. 3 hours in starting feeling nauseous, 7 hours in I felt like my throat was numb and someone was choking me. Then the night of I had the worst Migraine of my life and I have experience with migraines but this was the worst of the worst. It lasted 5 hours, called my dr and asked their advise. Now im slowly getting better. Definitely research this medication before taking because it is very very strong.

My doctor tried switching me from SSRI’s for my anxiety and depression and put me on Cymbalta. It made me so suicidal, I wanted to kill myself every day. Sure, I was depressed, that’s why I was on SSRI’s in the first place, but I never had such a strong urge to end my life. This medication severely reacted with me. I have never had a month filled with such dread and self-hate in my entire life. Immediately felt better once taken off it. I DO NOT RECOMMEND!!!!

Watch out for withdrawal symptom if missed a dose. I experienced “brain snaps”. When googled, they were from serotonin withdrawal…sounded like thumb and finger rub near ear. Article went on to say snap takes place when lateral shift of eyes to either side takes place. Phew. My anxiety is over, Just keep your eyes straight when they occur.

The side effects of this when you need to stop using it I can only describe as horrendous I’ve never experienced anything like it and I’m not kidding I didn’t or rather couldn’t get out of bed for 3 days sickness diarrhoea vertigo ringing and buzzing in my ear avoid using this if you can avoid it

Idiopathic PN in feet and radiculopathy (nerve pain and stiffness in legs) due to serious L5-S1 nerve impingement. Got hard walking. No depression or anxiety. Only 4th day. Very woozy during day and a bit amped and hard to sleep at night. Taking it in the evening. PN and radiculopathy condition seem to be improving. No significant side effects yet, maybe a touch of constipation. Has anyone tried medical MJ tincture in the evening to neutralize evening head buzz?

I wish I knew about duloxetine earlier. This medication actually works. I feel calm, the chatter has stopped, suicide thoughts are gone. Into week three now and I am actually starting to feel happier within myself. I am no longer short tempered, cranky. I so happy I came across duloxetine....

Have started on 30mg for pain related to muscle necrosis, and it doesn't work for me at all. The first week I was feeling constantly nauseous, could barely eat and had severe diarrhoea. It made me constantly shake and sweat profusely. My doctor wants to increase the dose to 60mg and i have had to say no. This medication is AWFUL

DO NOT TAKE THIA DRUG! It helped with stopping anxiety but it has horrible withdrawal effects when you stop taking it! It was like a sedative while taking it. I slept 12-14 hours a day and had no energy to do anything. It’s been 2.5 months since I stopped taking it and I’ve had HORRIBLE HEADACHES for days and ANXIETY THROUGH THE ROOF! It is scary just to drive my car. I am still getting brain zaps and dizziness. I told my oncologist office dont ever prescribe me anything like this again!

I am not sure if this medicine is causing feeling sick or not but it is one of the side effects. Wondering if anybody else has had this side effect.

I was prescribed Cymbalta (Dytrex equivalent) a couple of years ago for my Rheumatoid Arthritis ( in conjunction with another medication for my RA). My Doctor said that Cymbalta is a very safe drug with very little side-effects; he didn’t mention anything about the withdrawal side-effects (I’m not sure if he really even knew the full extent of the withdrawal symptoms). Now, in 2022, my Arthritis is under control so I am happy to gradually wean off the Cymbalta. A couple of weeks into weaning off this medication, I was already going through hell, and I haven’t even taken it for a long period like some of the poor people who have commented in the last few years. I suffered from constant diarrhoea, nausea, dizziness, brain-zaps, sleeping problems. A few months further on into weaning off the Cymbalta, things were starting to get worse - I was getting constant ‘Hyperhidrosis’ (severe sweating of the heels, palms, underarms) - to the point that I was losing a lot of electrolytes in my body, and went to Emergency because I didn’t know what was wrong with me and why I wasn’t feeling better (I also had a viral cold at the same time, to complicate things more); I also realised that I was getting serious ‘Anxiety attacks’. As a normal thing, I just get a ‘little’ bit of anxiety at times, but Cymbalta has made everything so bad! I get anxiety attacks especially at night when I’m alone, I feel so scared to be alone by myself, I suddenly have an uncontrollable fear of death, fear of everything that threatens my safety and my life, I can’t even explain why I fear, I just feel that I fear, without even knowing what exactly it is that I fear, things are just so literally crazy! I don’t feel like I am myself, my head always feels so cloudy, unclear, fuzzy; I feel a deep sense of hopelessness, depression, lacking motivation in doing anything, even the things that I use to enjoy doing before; I have memory loss, I use to be a very alert and switched-on type of person, now not anymore. I feel my life has been ruined, and my good future has been prematurely taken away from me. I don’t know if this anxiety attack will ever go away entirely, I don’t know if I will ever have a normal life like I did pre-Cymbalta. I pray for all those who have and will suffer from this drug, and can only hope that eventually the withdrawal effects may miraculously taper off. If I knew how bad the withdrawal side-effects were, I would ‘NEVER’ have taken Cymbalta, I would have tried some other drug for my RA. The withdrawal symptoms are so bad that it’s not worth taking Cymbalta because in the process you will gain more serious problems, some of them may even last for a long time, whether they may be permanent, I do not know. It is my hope, for the sake of us all, that they are not permanent withdrawal effects, such as my very scary and debilitating and paralysing ‘anxiety attacks’. May we all help and support each other through this hellish journey. Read More Read Less

Please don’t be put off trying this medication by all the bad reviews. I’ve had chronic generalised anxiety and panic disorder all my adult life, and I’ve tried every ssri and also venlafaxine xr. This is the first drug I’ve tried that has not only helped massively but I don’t have any horrible side effects from. It’s literally saved my life. I still have slight anxiety but it’s manageable, and I don’t panic anymore. I actually feel I can live my life and feel normal now. It’s also the only drug that has given me a sort of sex drive back and normal orgasms again. Please don’t be afraid to try it. It’s worked amazingly for me. I wouldn’t be without it. Give it time, starting any new medication can be a bit rough, but it’s honestly a miracle worker. Read More Read Less

I am a 74 year young female. I have suffered with muscular pain and extreme lower back and leg pain for years. Most of my lifetime. I have been on I do believe every antidepressant there is out there, including getting injections. After speaking to my pharmacist my doctor agreed for me to try Cymbalta. Tonight will only be my third pill. I was a little concerned about the side effects. So far none except tiredness. First pill took in the morning as I already have insomnia for years. That day very tired so the next was a nighttime try. Very restless sleep but going to try again tonight. As I said I had i Sleep deprivation before this med. so far excellent and I’m glad I tried. To not have this pain throughout my day will be heaven. I will update in a few weeks. So far minimal side effect . Please try this one. Read More Read Less

I was terrified to take this medication after reading the bad reviews. I’m so happy that I did. The first week I felt “high” as if I had taken cold medication. Terrible diarrhea and hot and cold chills. Although they were very frustrating none of the side effects were bad enough that I couldn’t make my way to work. I take 30mg at night before bed (with a gaba/melatonin/magnesium supplement and I have no problems sleeping at all. Come morning I feel a little tired still but nothing I can’t deal with. I for sure wouldn’t be able to take this medication during the day. Haven’t noticed any sexual side effects yet. Within a couple of days of taking this medication my anxiety and depression have almost completely gone. It has been an absolute life saver for me. About a week and a half after starting the medication I started to develop a rash on my face and neck. Unsure if the rash was related I stopped taking the medication for two days. It went away. I’ve been back on them for about a week and it hasn’t come back yet. I highly recommend this drug. I had tried so many other things and had such bad reactions but this drug literally saved my life. Read More Read Less

I was lucky I started having bad side effects after the first dose of this horrendous medication . Hallucinating , loose bowel movement, feeling spicy like I wasn’t in the room.after calling my doctor he told me to keep on the medication so I took the second dose the next day & the side effects got worse I ended up in the emergency room 14 hours after I took the second dose Heart beating out off my chest ,hot & cold sweats,agitated, constipated ,low blood pressure, not knowing who or were I was ,struggling to breathe ,horrible uncontrollable body shaking I spent 1 day in hospital I stopped after that 2nd dose I called my doctor & told him no more medication like duloxotine I have been off them for a few days now I’m only taking Ibuprofen now.to manage the back pain The pain is still there . But I put up with the pain Instead of all the side effects from this hideous medication. Please I just want people to not take this medication It’s not worth it Read More Read Less

I started to take Duloxetine 20mg for neuropathic nerve pain for about two months and so it worked fairly well. Then my mPCP suggested that I try 30 mg and my digestive system completely shut down and it caused chronic constipation. Plus it made me pee a gallon at night and my skin especially on my face felt like concrete. So I stopped it.

I suffer from bipolar disorder II, adhd, and fibromyalgia. I take 15 grains, not grams, but individual grains in the morning and 15 grains at night, 12 hours apart. I also take Vimergy MTHR which is a folate and a b12. I also take lemon balm and cat's claw. The duloxetine at this level has helped me so much with the depression. I take such a small amount due to the fact that my provider wanted me to make sure it wouldn't flip me into mania. It doesn't and it has taken me out of one of the worst depressions I have ever had last fall and I continue to not have depression. I have to take it 12 hours apart because it will start to wear off so I have to be sure to take it. It takes away my body pain and depression. Doctors always raise and eyebrow when they find out that I am taking such a small amount but for me it works, and I need to take it. Everyone is different. Read More Read Less