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3.8 Overall Rating

Effectiveness

Ease of Use

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Most voted positive review

2 People found this comment helpful

I am not through with treatment, I have had 3 so far, and I can see glimpses of not being depressed. My suicidal thoughts that were nearly constant are few and far between. I gave it a low score on ease because of having to stay at the doctors office. It would be nice to do it at home. But I can see why the patient has nothing to do with getting the medication because I could see the addictive pr...

Most voted negative review

4 People found this comment helpful

Interesting drug that is stronger than straight Ketamine. The main problem I have is with it running down my throat. NASTY. That can make you puke.A 28mg dose doesn't do much but make you relaxed. Second dose 5 minutes later starts things rolling. You start to really feel it after several minutes. The third dose is where the fun begins. For the most part the experience is good, especially comi...

Shared reviews and ratings

Hate ketamine | 45-54 | On medication for 2 to less than 5 years | Caregiver
2/23/2024
Condition: Additional Medications to Treat Depression
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I am the about to be exhusband of a lady who started taking this by IV two years ago and it’s only bankrupt our family and now although she’s fifty years old, she’s decided it’s time to blow her family up, go move in with her elderly parents, quit her six figure job, go on food stamps and welfare and now divorce, now hanging out with old divorced friends at the bar and also began drinking after probably fifteen years of not drinking at all. It seems evident to everyone but her and her crazy mother who thinks she’s normal acting that it’s the ketamine.Read More Read Less

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Courtney R. | 25-34 | Female | On medication for 1 to less than 2 years | Patient
12/2/2023
Condition: Additional Medications to Treat Depression
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I took this medication for a year, 2 days every week. My doctors office wound up having some issues and caused them to have to move. During their move they no longer could take my insurance, so i kinda got thrown on the street cold turkey. I was given the chance to go to another place that offered treatments and i went to check it out but i was very uncomfortable with the atmosphere, so i just quit. Before i started i had suicidal thoughts every single day! I woke up thinking is this the day? and would sleep all day long, i wouldn't even get up to eat. After not eating i lost almost 100 pounds and was so weak i couldn't brush my hair and had to shave the underneath. I have now been off this medication for a full year and i have never felt better in my life! I AM IN NURSING SCHOOL!!! I'm going to get a license to be a psychiatric nurse practitioner because my life was saved by one! I have had some bad thoughts but nothing like the ones i had before treatment. I have goals and I don't feel hopeless! I struggled with TRD and CPTSD and Anxiety. I probably tried well over 10 different medications and nothing even touched the sadness! I'm so thankful for this medication and my psychiatrist! Read More Read Less

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LIFE_Idecided | Female | On medication for 1 to 6 months | Patient
11/21/2023
Condition: Other
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I have CPTSD, MDD, and generalized anxiety. I was having intrusive suicidal thoughts and was sleeping, unable to get out of bed majority of the time. Initially I did 2 sessions a week of spravato and am now doing once a week. I am 3 months into treatment, returned to my full time job after being on short term disability. Almost immediately I started feeling better. Was able to do self care and hygiene that I had stopped doing as one should. I guess if you are scared of gaining a different perspective this treatment probably isn’t for you. I don’t get motion sickness and have tolerated the treatments well. Honestly, it has been worth every dime in my opinion to stop spending every waking minute thinking of suicide. I encourage anyone with MDD to give it a try. Be open minded and just relax and enjoy the disassociation. It felt great to get out of my own head. I finally feel like myself again. Read More Read Less

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GeDixie1040 | 45-54 | Female | On medication for 1 to 6 months | Patient
11/21/2023
Condition: Additional Medications to Treat Depression
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I just finished 4 weeks of Spravato, twice a week. I stayed at 56mg for most of the treatments because I saw positive results within two treatments, and had a bad dissociative reaction on 84mg. Each session had slightly different side effects. A couple I was nauseated and vomited and had mild dissociation, while with others I had moderate, pleasant dissociation, hyper-focused, dizziness, feeling drunk, and still others I sailed through feeling lightly buzzed. The nursing staff was amazing, and their care for me was bar-none! I feel better than I've felt in my life. I finally don't dread my existence and future. I don't worry or take to heart people's negative words about me. I feel level. Like calm. I used to complain about feeling like a fizzing soda all the time. A majority of that is gone. This stuff is amazing. I'm glad I stuck with it and didn't quit after my bad reaction. Read More Read Less

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Marie Arsenault | 65-74 | Female | Patient
11/10/2023
Condition: Other
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

No antidepressants or bipolar drugs ever worked for me in 45 years For the first time in my life I have hope

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Me714! | 55-64 | Male | On medication for less than 1 month | Patient
11/4/2023
Condition: Additional Medications to Treat Depression
Overall rating 2.7
Effectiveness
Ease of Use
Satisfaction

I have a question. Has anyone experienced loud ringing or buzzing in the ear after treatments. TYIA

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Louise | 45-54 | Female | On medication for 1 to 6 months | Patient
9/14/2023
Condition: Additional Medications to Treat Depression
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

After reading the reviews I was scared to death to start treatment. I have now had about 6 treatments and have never felt better. I take Zofran before just incase I have nausea but other than that there are no problems. For me the taste of the nasal spray is no more worse than Afrin. I feel ligh headed and giddy but I just close my eyes and doze for 2 hours and then I'm done. For me, it's been a piece of cake. No regrets.

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Curt N. | 65-74 | Male | Patient
8/19/2023
Condition: Additional Medications to Treat Depression
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Easy ans safe process. Best done with a therapist with who you are comfortable and relaxed/

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BryM | 65-74 | Female | Patient
7/12/2023
Condition: Additional Medications to Treat Depression
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

I like what the Spravato does to lift my spirits. It does, however, cause extreme skin irritation for me and I am going to have to discontinue its use. This happened after I was on it for about three months, but I've definitely developed some kind of allergy to it. I am on the final month of doses every other week, but I had a reaction two weeks ago, and I had a treatment this morning and am already having a reaction. So, the allergy is escalating and is worse with each use. I am bright bright red from the back of my neck down to my thighs. I have big welts, itch all over, and had to buy a benedryl creme to try to minimize it. Be careful with the drug folks. I think the build up is too much for my system, and I'm basically allergic to only one medication...diphenoxylate hydrochloride and atropine sulfate monohydrate. Since Spravato has some hydrochloride in it, I assume that's what's giving me the rash. I'm not a doc., so I don't know, but it makes sense to me. I won't be able to tolerate this reaction a third time.Read More Read Less

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Burnt out in OH | 45-54 | Female | On medication for 1 to 6 months | Patient
4/4/2023
Condition: Additional Medications to Treat Depression
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I have been suffering with various degrees of depression to for the better part of 20 plus years. For the past year I have been on a steady decline to the point I have let my appearance go, my housework go, no longer want to go anywhere or do anything, basically isolated myself. Which in turn has had a severe negative impact at work and on my family. When I heard about spravato, I thought, Finally! I was so eager to finally feel something other than complete despair. I took a leave of absence from work, found a provider, got approved and began treatment. I just had my 7th dose yesterday. I can't say I feel any different than from before I started. I know I should at least start to feel better, but I just don't. I have tried to force myself to go get my hair done, actually take my kids out to a nice dinner... But that just leaves me feeling worse. I just can't feel any enjoyment. Aside from not feeling relief of my symptoms, the medication itself is wicked. I have never done any kind of "drugs" in my life. Never even smoking pot. I absolutely hate the high feeling. It's terrifying to me. The first two doses at the lower dose were bad, but when I had to move up to the 84 mg dose, it is unbearable. I can only like it to stories I read and pictures I've seen about the Russian sleep experiment. I just feel so disconnected, skeletal and manic. I know a side effect is disassociation, but not having anything to compare it to, it's the worst feeling I have ever had. It lasts for about 30-45 minutes then I start to come down but feel dizzy and confused for the rest of the day. I get my treatment at 3:30. I usually have a headache the next day. I did tell my psychiatrist how horrible it makes me feel, but he insists I need the 84 mg dose according to studies. This is on top of trying to coordinate rides living about 40 miles from the Dr office. Then to have to explain why I need to go twice a week and why I feel so bad afterward. I don't want anyone to know what I'm going through as I do not have a very good support system. I have to return to work next week and am just dreading it as I do not feel much if any different. I will stick it out and finish my twice weekly treatments this week and the next once weekly treatments over the next four weeks "just in case" it may just take longer to work for me and I want to finish what I started but so far the cons have outweighed any pros. I'm just feeling so defeated. I had such high hopes and am scared to death that this will all have been for nothing. Even more scared of "so what's next"? Read More Read Less

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Khurshid khan | 45-54 | Male | On medication for less than 1 month | Patient
3/17/2023
Condition: Additional Medications to Treat Depression
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I have used it for 2 weeks and I was getting hope it will work as I feel it.but unfortunately I had to stop it because of the side effects of rashes and eczema and inflammation. And chest pain

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Jay D. | 35-44 | Male | On medication for less than 1 month | Patient
3/6/2023
Condition: Additional Medications to Treat Depression
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

My first administration was this morning. I didn't notice any side effects, except for a slight maybe high feeling, but that didn't last more than 4 or 5 minutes. It sort of numbed up my face a little it felt like. Other than the taste running down my throat, my only complaint would be the time you have to wait after the medication being administered, and the task of finding a driver. I feel less drab already, and hope all continues to improve. There have been weeks I didn't have energy to bathe or get out of bed for anything other than to urinate and get a quick drink. Antidepressants help only to make these episodes less lengthy, and left residual daily depressive symptoms with fatigue, brain fog, and memory issues. Read More Read Less

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Rocky | 25-34 | Female | On medication for 6 months to less than 1 year | Patient
1/13/2023
Condition: Additional Medications to Treat Depression
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I was very skeptical as nothing seemed to help consistently. I had multiple hospital stays, a suicide attempt, and held on for years. The last major depressive episode I had I was extremely suicidal and the medication they tried I was severely allergic to. I felt hopeless. I had no more fight. I didn’t want to live anymore because things just never seemed to stay ok. My psychiatrist said there is a newer treatment and I think you should try it. I was like great something else to try and fail. However that is until now. I have been on Spravato 10 months and it has been a life saver. I have been more stable than I ever have in my life. I am able to fully function. I have taken 2 days off work for mental health reasons this year versus 14-18 before Spravato. My quality of life has changed. Now… I hate going because I hate how it taste, I am not fond of disassociating/ effects, and the 2 hour wait isn’t ideal. However, I will take every single thing that happens in that 2 hours if the rest of my life is manageable. The only side effects I have are during the treatment duration. I don’t have any medication side effects in the hours or days later. The time between treatment is based on how I am doing with symptoms. I have gone 6 weeks between treatments and during tough periods as often as once a week. It is about maintaining communication with the providers and being honest with how you are feeling. I don’t recommend this medication to ever be prescribed outside of a medical facility as the effects during that 2 hours need monitored. I know for me, each time I go the symptoms vary regarding the dissociation. Sometimes it’s intense and other times it’s minimal. Read More Read Less

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Dennis | 55-64 | Male | On medication for 1 to 6 months | Patient
10/1/2022
Condition: Additional Medications to Treat Depression
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

This is the first thing to even dent my severe depression in 30 years. It won’t solve your problems. It won’t make you happy, whatever that means. But the horrible gray fog of numbness has lifted. Ease of use is low because it’s administered by the doctor and you must stay 2 hours, and you’re not allowed to drive home.

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MDDBPD | 35-44 | Female | On medication for less than 1 month | Patient
9/24/2022
Condition: Additional Medications to Treat Depression
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

I heard about this Rx awhile ago but thought it was too new to ever be covered by insurance and forgot about it. I've been in some sort of therapy since I was 8 if not earlier. I have Major Depressive Disorder, Borderline Personality Disorder, PTSD, Anxiety and the list keeps going. I'm 44 years old now. Life has seriously gotten unbearable for me. Thoughts of suicide, sleeping to escape, isolating, hating myself and the world... You start to lose any hope the older you get, the more meds you've tried, the more of them that do nothing. A few years ago I went on Viibryd. It helps a teeny tiny bit. Only one that does. I've been searching for something and came across an ad on Facebook for a place by me offering Spravato. Then I remembered.... It's 100% covered by my insurance. Not even a co-pay. I would prefer the IV but I'll take any option at this point. The insurance was a huge hurdle. They did deny though I was outright qualified. I have UnitedHealth via Medicare and Medicaid. Submitted again and eventually it was approved. I lost my job because of the hours required, they weren't willing to work it out with me but it really became like I do this or kill myself so I quit. Today was my first visit. I keep asking myself if this is real or a placebo effect? Anyway, I got there. I filled out how am I doing paperwork, I took a spray to each nostril. Not fun but okay. Waited 5 minutes and repeat. Then I started giggling and feeling floaty. Then happy and silly. I had some trouble walking when I had to go to the bathroom but it's like my legs weren't... Right lol. That wore off in like 45 minutes. Then it was simply like things were....good. I felt good. I remain feeling good. I was telling my bf how I could see why things happened maybe for our benefit that had been negatives lately and he started to tear up. He looked at me and said you chose hope just now. He said I never do. Maybe it's placebo. I dunno. I don't think it is though. I'm excited. I'm seriously hopeful. I haven't felt this way I think ever? I don't know that I know how to be happy. It'll be an adventure. I hope you all find yours. The times I wish were offered in the evenings so it didn't effect peoples jobs. That's a serious problem. I mean I don't mind being there the 2 hours. The driver thing... I think they should allow in our day and age for people to Uber back and forth at least. Not all of us have others to ask for help. My 2 cents.Read More Read Less

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Remrque | 65-74 | Male | On medication for less than 1 month | Patient
8/12/2022
Condition: Additional Medications to Treat Depression
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I think to note that most of the negative comments are more to do with logistics and process ( the 2 hour treatment time, insurance, etc. ) than the actual efficacy of Spravato itself. After just 2 sessions, I can say that something is happening and it's on the positive side. I've been in and out of TRD for 50 years and though never had any suicidal ideation, it's still feels terrible. Everything is relative. I find the 2 hour process actually relaxing and, at least the first 90 minutes, necessary. You really are not as mobile as you usually are. Everyone's experience with this will be felt in a uniquely individual way. Perception of what you thought was one thing appears in a more realistic light and, therefore, usually a better light, hitherto obscured. That's what, so far, has been the highlights for me. Energy and appetite have inched into more positive territory, as well. Looking forward to week 2. Good luck to all.Read More Read Less

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Courtney Blair | 65-74 | Female | On medication for 1 to less than 2 years | Patient
8/8/2022
Condition: Additional Medications to Treat Depression
Overall rating 2.7
Effectiveness
Ease of Use
Satisfaction

Side effects are as described. I used it for exactly 1 year. It may have helped initially but the majority of the 12 months I did not improve. I have TRD and anxiety with panic attacks. It seems like none of the medications work for me. Sidebar: I've had these conditions since early childhood

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Had Enuff | Female | On medication for 1 to 6 months | Patient
8/8/2022
Condition: Additional Medications to Treat Depression
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

Living rurally and having to travel 120 kms round trip and have to rely on someone to take you home afterwards. I am not on any other medication for my mental health. Had 8 treatments so far and I am still sleeping all day with no incentive to be alive. Ready to withdraw from the trial as its a waste of time resources and energy.

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JAS | 45-54 | Male | On medication for 6 months to less than 1 year | Patient
6/29/2022
Condition: Additional Medications to Treat Depression
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

Spravato gave me a much needed boost with the first dose. It didn’t completely alleviate my depression but it definitely got me out of a hopeless state. I was sleeping 24 hours a day for 7-8 months with only breaks to eat and use the bathroom. After the first dose of Spravato, I was able to play with my dog outside. This drug will give you a kickstart but probably won’t bring you all the way out of the depression alone. The downside is that you will need to find a ride to the doctor’s office. Then you have to wait 2 hours before you can be picked up. I am on wellbutrin, pristiq and abilify. I see my psychiatrist once a month and a counselor weekly. The Spravato definitely gave me enough of a boost to be able to start to recover with the help of counseling and other antidepressants.Read More Read Less

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Anne | 0-2 | Female | On medication for 1 to less than 2 years | Patient
6/28/2022
Condition: Additional Medications to Treat Depression
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

I’ve had a good response for which I’m grateful. My doctor and his staff are excellent. Because of my medical history I was eligible under my health insurance’s unusually narrow criteria and approved quickly and have continued to receive preapprovals for weekly treatment. Although each treatment is only $20 out of pocket, I’m not thrilled that each treatment is so expensive—I’ve no problems with the seemingly high cost of the office visit, considering that I’m in there for 2+ hours and it makes sense in terms of overhead, but I’m uncomfortable with the cost for what is a very expensive device to administer a generic existing drug with decades of safe use. I’ve not been able to progress to less frequent treatments and while cheaper than inpatient treatment, the $75K a year is a great deal of money. I find myself participating in what I find worst about the pharma industry.Read More Read Less

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