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How does Willebrand factor deficiency cause blood-clotting problems?

ANSWER

A relatively common condition called von Willebrand factor deficiency makes blood clots form slowly because your body doesn't have enough of a specific protein to trigger the clotting process. It's usually mild.

SOURCES:

Merck Manual: "How Blood Clots."

World Federation of Hemophilia: "The clotting process."

American Stroke Association: "Anti-Clotting Agents Explained."

Lipe, B. Circulation, Oct. 4, 2011.

Furie, B. New England Journal of Medicine, 2008.

Hoffman, R. Hematology: Basic Principles and Practice, 5th edition, Churchill Livingstone Elsevier, 2009.

Fiumara, K. Circulation, 2009.

Reviewed by Gabriela Pichardo on January 20, 2020

SOURCES:

Merck Manual: "How Blood Clots."

World Federation of Hemophilia: "The clotting process."

American Stroke Association: "Anti-Clotting Agents Explained."

Lipe, B. Circulation, Oct. 4, 2011.

Furie, B. New England Journal of Medicine, 2008.

Hoffman, R. Hematology: Basic Principles and Practice, 5th edition, Churchill Livingstone Elsevier, 2009.

Fiumara, K. Circulation, 2009.

Reviewed by Gabriela Pichardo on January 20, 2020

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