blue eye close up
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Eye Cancer

Got blue, green, or gray eyes? You’re more likely than your brown-eyed friends to get a specific cancer of the eye called uveal melanoma. Your chances are still low, though -- only 2,500 people in the U.S. get it each year.

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woman with brown eyes looking in camera
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Researchers found that people tend to rank brown-eyed faces more trustworthy than others. But the study went on to say that facial features common to folks with brown eyes were more likely to give people feelings of trust.

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man using lancelet
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Blood Sugar Issues

While more research is still needed, a 2011 European study suggests that a combo of blue eyes and fair skin puts you at a higher risk of getting type 1 diabetes. 

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music concert crowd
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Hearing Loss

Studies show that in a loud environment, brown-eyed people have less hearing loss than people whose eyes have a blue hue. It's believed to be because brown-eyed folks have more melanin (the pigment that gives your skin, hair, and eyes their color) in their eyes and ears. That gives them a bit more protection when noise levels go up.

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woman holding glass of alcohol
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Drink Dependence

Not only are you more likely to drink alcohol if your eyes are blue, you’re also at a higher risk of becoming addicted to it, according to a 2015 study. It's possible that genetic linkages and othert variables may also be involved.

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woman hugging pillow
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This is when tissue that normally grows inside your uterus grows outside of it. When it invades organs like the bladder and bowel, it's called deep infiltrating endometriosis (DIE). Women who have DIE have blue eyes more than any other color. Experts think the genes that control eye color may link to the ones that cause DIE.

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man in talk therapy
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Response to Therapy

Your eye color can play a role in what type of behavior therapy works best for you. Dark eyes can mean you’ll have better results in treatment that's more rigid. Meanwhile, light-eyed folks are more likely to respond to a program that changes as they do, at their pace.

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different sized pupils on woman
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Different Dilations

One out of 5 people has naturally different-sized pupils -- one smaller than the other. But sometimes, mismatched pupils can be a sign of a health issue, like a nervous-system problem, stroke, or infection. 

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hands with vitiligo
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If you have blue eyes, you're less likely to have this condition that makes you lose skin color in blotches. Experts think it could be because some of the genes that help make eyes blue also lower your risk of getting the condition.

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eye with cataracts close up
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This vision-clouding condition is more likely to hit you if you have dark brown eyes, one Australian study says. Researchers believe that shade makes cataracts twice as likely.

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student looking over book
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Star Pupils

Studies are ongoing, but experts think that resting pupil size could be a sign of intelligence. Larger pupils tend to connect to a brain that works well.

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man with blue brown eyes
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Multicolored Eyes

Do you have a blue patch in your mostly brown eyes? It could be a symptom of Waardenburg syndrome. That genetic disorder can make you lose pigment in your hair, skin, and eyes. It can also cause deafness and unique facial features, like wide-set eyes and a wide nose bridge.

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man lining up golf shot
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Sports Skills

In movements done as a reaction -- boxing, hitting a ball, football defense -- those with brown eyes are more likely to shine. But if the action is one you control from start to finish, like bowling, golfing, or pitching a baseball, you’ve got a leg up if your eyes are blue. 

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woman in labor pain
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Pain Tolerance

Studying women in labor helped scientists learn what eye color may say about how much pain you can take. Their theory: Women with dark-colored eyes tended to show more distress during labor. They woke from pain more often, felt more pain at rest and when they moved, and were more likely to be depressed because of their pain.

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vision with black blur obstruction
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Macular Degeneration

An Australian study says people with light-colored eyes are twice as likely to get age-related macular degeneration. That's because less UV light is being absorbed by the iris, so more can get through to the retina and cause damage, This disease can cause vision loss.

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Sources | Medically Reviewed on 10/11/2019 Reviewed by Whitney Seltman on October 11, 2019


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Scientific Reports: “Genetic markers of pigmentation are novel risk loci for uveal melanoma.”

The Ohio State University Comprehensive Cancer Center: “Increased Eye Cancer Risk Linked to Pigmentation Genes That Dictate Eye Color.”

PLOS ONE: “Trustworthy-Looking Face Meets Brown Eyes.”

Diabetes/Metabolism Research and Reviews: “Blue eyes as a risk factor for type 1 diabetes.”

Hearing Research: “Eye color as a risk factor for acquired sensorineural hearing loss: a review.”

American Journal of Medical Genetics: “Eye color: A potential indicator of alcohol dependence risk in European Americans.”

Human Reproduction: “'Behind blue eyes': the association between eye colour and deep infiltrating endometriosis.”

Journal of Clinical Psychology: Eye color as a predictor of outcomes in behavior therapy.

American Academy of Ophthalmology: “What is Anisocoria?”

Nature Genetics: “Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants.”

Cognitive Psychology: “The relationship between baseline pupil size and intelligence.”

American Journal of Ophthalmology: “Iris color and cataract: the Blue Mountains Eye Study.”

National Organization for Rare Disorders: “Waardenburg Syndrome.”

Perceptual and Motor Skills: “Correlation of eye color on self-paced and reactive motor performance.”

Medscape: “Does Eye Color Predict Response to Pain?”

Clinical and Experimental Ophthalmology: “Iris colour, ethnic origin and progression of age-related macular degeneration.”

Reviewed by Whitney Seltman on October 11, 2019

This tool does not provide medical advice. See additional information.

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.