Medically Reviewed by Whitney Seltman, OD on November 03, 2021

Eye Cancer


Got blue, green, or gray eyes? You’re more likely than your brown-eyed friends to get a specific cancer of the eye called uveal melanoma. Your chances are still low, though -- only 2,500 people in the U.S. get it each year.



Researchers found that people tend to rank brown-eyed faces more trustworthy than others. But the study went on to say that facial features common to folks with brown eyes were more likely to give people feelings of trust.

Blood Sugar Issues


While more research is still needed, a 2011 European study suggests that a combo of blue eyes and fair skin puts you at a higher risk of getting type 1 diabetes. 

Hearing Loss


Studies show that in a loud environment, brown-eyed people have less hearing loss than people whose eyes have a blue hue. It's believed to be because brown-eyed folks have more melanin (the pigment that gives your skin, hair, and eyes their color) in their eyes and ears. That gives them a bit more protection when noise levels go up.

Drink Dependence


Not only are you more likely to drink alcohol if your eyes are blue, you’re also at a higher risk of becoming addicted to it, according to a 2015 study. It's possible that genetic linkages and othert variables may also be involved.



This is when tissue that normally grows inside your uterus grows outside of it. When it invades organs like the bladder and bowel, it's called deep infiltrating endometriosis (DIE). Women who have DIE have blue eyes more than any other color. Experts think the genes that control eye color may link to the ones that cause DIE.

Response to Therapy


Your eye color can play a role in what type of behavior therapy works best for you. Dark eyes can mean you’ll have better results in treatment that's more rigid. Meanwhile, light-eyed folks are more likely to respond to a program that changes as they do, at their pace.

Different Dilations


One out of 5 people has naturally different-sized pupils -- one smaller than the other. But sometimes, mismatched pupils can be a sign of a health issue, like a nervous-system problem, stroke, or infection. 



If you have blue eyes, you're less likely to have this condition that makes you lose skin color in blotches. Experts think it could be because some of the genes that help make eyes blue also lower your risk of getting the condition.



This vision-clouding condition is more likely to strike earlier if you have dark brown eyes, one Australian study says. Researchers believe that shade makes cataracts twice as likely. However, everyone will get cataracts eventually, no matter their eye color. 

Star Pupils


Studies are ongoing, but experts think that resting pupil size could be a sign of intelligence. Larger pupils tend to connect to a brain that works well.

Multicolored Eyes


Do you have a blue patch in your mostly brown eyes? It could be a symptom of Waardenburg syndrome. That genetic disorder can make you lose pigment in your hair, skin, and eyes. It can also cause deafness and unique facial features, like wide-set eyes and a wide nose bridge. 

It could also be a normal sign of an aging cornea called arcus sinilus.


Sports Skills


In movements done as a reaction -- boxing, hitting a ball, football defense -- those with brown eyes are more likely to shine. But if the action is one you control from start to finish, like bowling, golfing, or pitching a baseball, you’ve got a leg up if your eyes are blue. 

Pain Tolerance


Studying women in labor helped scientists learn what eye color may say about how much pain you can take. Their theory: Women with dark-colored eyes tended to show more distress during labor. They woke from pain more often, felt more pain at rest and when they moved, and were more likely to be depressed because of their pain.

Macular Degeneration


An Australian study says people with light-colored eyes are twice as likely to get age-related macular degeneration. That's because less UV light is being absorbed by the iris, so more can get through to the retina and cause damage, This disease can cause vision loss.

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Scientific Reports: “Genetic markers of pigmentation are novel risk loci for uveal melanoma.”

The Ohio State University Comprehensive Cancer Center: “Increased Eye Cancer Risk Linked to Pigmentation Genes That Dictate Eye Color.”

PLOS ONE: “Trustworthy-Looking Face Meets Brown Eyes.”

Diabetes/Metabolism Research and Reviews: “Blue eyes as a risk factor for type 1 diabetes.”

Hearing Research: “Eye color as a risk factor for acquired sensorineural hearing loss: a review.”

American Journal of Medical Genetics: “Eye color: A potential indicator of alcohol dependence risk in European Americans.”

Human Reproduction: “'Behind blue eyes': the association between eye colour and deep infiltrating endometriosis.”

Journal of Clinical Psychology: Eye color as a predictor of outcomes in behavior therapy.

American Academy of Ophthalmology: “What is Anisocoria?”

Nature Genetics: “Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants.”

Cognitive Psychology: “The relationship between baseline pupil size and intelligence.”

American Journal of Ophthalmology: “Iris color and cataract: the Blue Mountains Eye Study.”

National Organization for Rare Disorders: “Waardenburg Syndrome.”

Perceptual and Motor Skills: “Correlation of eye color on self-paced and reactive motor performance.”

Medscape: “Does Eye Color Predict Response to Pain?”

Clinical and Experimental Ophthalmology: “Iris colour, ethnic origin and progression of age-related macular degeneration.”