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Can antidepressants treat fibromyalgia?

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Antidepressants are also sometimes prescribed to help people manage fibromyalgia symptoms:

  • Tricyclic antidepressants. By helping increase levels of the brain chemicals serotonin and norepinephrine, these medications may help relax painful muscles and enhance the body's natural painkillers.
  • Selective serotonin reuptake inhibitors (SSRIs). Your doctor may prescribe one of these types of antidepressants by itself or in combination with a tricyclic antidepressant. SSRIs prevent serotonin from being reabsorbed in the brain. This may help ease pain and fatigue.

SOURCES:

Mease, P. , Spring 2008; vol 18: pp 26-35. The Pain Practitioner

National Center for Complementary and Alternative Medicine: “Fibromyalgia and CAM: At a Glance.”

National Institute of Arthritis and Musculoskeletal and Skin Diseases: “Questions and Answers about Fibromyalgia.”

WebMD Medical Reference: “What is Fibromyalgia?;” “Fibromyalgia Medications;” “Fibromyalgia and Exercise;" “Fibromyalgia Treatments;” “Fibromyalgia and Alternative Treatments;” and “Herbs and Supplements for Fibromyalgia.”

National Fibromyalgia Association.  

WebMD Health News: "A Blood Test for Fibromyalgia?"

Reviewed by Carol DerSarkissian on April 27, 2019

SOURCES:

Mease, P. , Spring 2008; vol 18: pp 26-35. The Pain Practitioner

National Center for Complementary and Alternative Medicine: “Fibromyalgia and CAM: At a Glance.”

National Institute of Arthritis and Musculoskeletal and Skin Diseases: “Questions and Answers about Fibromyalgia.”

WebMD Medical Reference: “What is Fibromyalgia?;” “Fibromyalgia Medications;” “Fibromyalgia and Exercise;" “Fibromyalgia Treatments;” “Fibromyalgia and Alternative Treatments;” and “Herbs and Supplements for Fibromyalgia.”

National Fibromyalgia Association.  

WebMD Health News: "A Blood Test for Fibromyalgia?"

Reviewed by Carol DerSarkissian on April 27, 2019

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What medications are prescribed for fibromyalgia?

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