Weight Changes Tied to Older Women's Fracture Risk

Study found just a 5 percent change in weight may affect postmenopausal bone health

By Robert Preidt

HealthDay Reporter

WEDNESDAY, Jan. 28, 2015 (HealthDay News) -- The risk of broken bones increases with both weight gain and loss in older women, according to a new study.

These findings challenge the widely held belief that weight gain protects older women against fractures, the researchers said.

The study included data from more than 120,000 healthy postmenopausal women in the United States. The women were between the ages of 50 and 79 years old. Their health status was followed for an average of 11 years.

A weight loss of 5 percent or more was associated with a 65 percent higher risk of hip fracture, according to the researchers. They also found a 9 percent higher risk of upper limb fracture, and a 30 percent higher risk of central body fracture (hip, pelvis and spine) with weight loss.

A weight gain of 5 percent or more was linked to a 10 percent higher risk of upper limb fracture and an 18 percent higher risk of lower limb fracture, the study found.

The study wasn't designed to prove that weight loss or gain was responsible for the fractures, only that there was an association between these factors.

The investigators also found that unintentional weight loss was associated with a higher risk of hip and spine fractures. On the other hand, intentional weight loss was associated with a higher risk of lower limb fractures, but a lower risk of hip fractures.

The study, by Carolyn Crandall, a professor at the University of California, Los Angeles David Geffen School of Medicine, and colleagues was published Jan. 27 in the journal BMJ.

It's the first study to examine how weight changes affect older women's fracture risk in different parts of the body, and offers important information for doctors, the study authors said in a journal news release.