This is the big one: 735,000 people have one every year. A 50-year-old man has a 1 in 2 chance of getting heart disease at some point. The most common signs are chest pain, shortness of breath, and pain in your back, shoulders, or neck. You might also feel sweaty, dizzy, or like you’re going to throw up. Your risk is lower if you’re at a healthy weight, don’t smoke, and get regular exercise.