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How are stem cells used to treat heart failure?

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In clinical trials researches are testing several methods of giving people stem cells to treat heart failure:

Intramyocardial injection: Cells go right into the heart muscle, usually during another procedure like open-heart surgery, bypass surgery, or implanting a pacemaker.

Intracoronary infusion: A catheter puts cells into your coronary artery.

Intravenously: Cells go right into the bloodstream through a needle placed in a vein.

SOURCES:

International Society for Stem Cell Research: “Heart Disease,” “Types of Stem Cells,” “About Clinical Trials,” “Stem Cell Research: What to Ask.”

National Institutes of Health: “Mending a Broken Heart: Stem Cells and Cardiac Repair,” “Can Stem Cells Repair a Damaged Heart?” “Stem Cell Basics,” “NIH Clinical Research Trials and You.”

Current Cardiology Reviews : “Cellular Therapy for Heart Failure.”

U.S. National Library of Medicine: “ClinicalTrials.gov.”

U.S. Food and Drug Administration: “Consumer Information on Stem Cells.”

Circulation Research: “Cell Therapy for Heart Failure,” “Safety and Efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Patients With Heart Failure: A Phase 1/2 Randomized Controlled Trial (RIMECARD Trial).”

The Lancet : “Ixmyelocel-T for patients with ischaemic heart failure: a prospective randomised double-blind trial.”

Reviewed by Suzanne R. Steinbaum on October 14, 2017

SOURCES:

International Society for Stem Cell Research: “Heart Disease,” “Types of Stem Cells,” “About Clinical Trials,” “Stem Cell Research: What to Ask.”

National Institutes of Health: “Mending a Broken Heart: Stem Cells and Cardiac Repair,” “Can Stem Cells Repair a Damaged Heart?” “Stem Cell Basics,” “NIH Clinical Research Trials and You.”

Current Cardiology Reviews : “Cellular Therapy for Heart Failure.”

U.S. National Library of Medicine: “ClinicalTrials.gov.”

U.S. Food and Drug Administration: “Consumer Information on Stem Cells.”

Circulation Research: “Cell Therapy for Heart Failure,” “Safety and Efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Patients With Heart Failure: A Phase 1/2 Randomized Controlled Trial (RIMECARD Trial).”

The Lancet : “Ixmyelocel-T for patients with ischaemic heart failure: a prospective randomised double-blind trial.”

Reviewed by Suzanne R. Steinbaum on October 14, 2017

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