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How can diabetes medications cause heart failure?

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Diabetes medications. Your body gets rid of metformin through your kidneys, so it isn’t a good choice if your kidneys don’t work like they should. Thiazolidinediones (pioglitazone, rosiglitazone) cause fluid retention and weight gain in people with heart failure and make people who don’t have it more likely to get it. Doctors aren’t sure why, but dipeptidyl peptidase-4 inhibitors (alogliptin, linagliptin, saxagliptin, sitagliptin) seem to send people with heart failure to the hospital. Never stop taking a medication without your doctor’s OK, though.

SOURCES:

Mayo Clinic: “Heart Failure: Definition.”

Drug Safety : “Heart failure induced by non-cardiac drugs.”

Circulation : “Drugs That May Cause or Exacerbate Heart Failure.”

Reviewed by James Beckerman on July 21, 2017

SOURCES:

Mayo Clinic: “Heart Failure: Definition.”

Drug Safety : “Heart failure induced by non-cardiac drugs.”

Circulation : “Drugs That May Cause or Exacerbate Heart Failure.”

Reviewed by James Beckerman on July 21, 2017

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How can blood pressure medicine cause heart failure?

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