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What medicines can lead to heart failure?

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Several drugs can lead to heart failure or make it worse, including:

  • Antidepressants -- citalopram (Celexa) and tricyclic antidepressants
  • Antifungal drugs -- amphotericin B (Ambisome, Amphotec) and itraconazole (Sporanox, Onmel)
  • Drugs that affect your appetite
  • Asthma medicines -- albuterol (Proventil, Ventolin), bosentan, and epoprostenol
  • Blood pressure medicines -- alpha-blockers and calcium channel blockers
  • Chemotherapy drugs used to treat cancer
  • Diabetes drugs -- metformin (Glucophage, Glumetza)
  • Epilepsy drugs -- carbamazepine (Tegretol) and pregabalin (Lyrica)
  • Heart rhythm drugs
  • Non-steroidal anti-inflammatory pain relievers (NSAIDs)
  • Migraine medicines -- ergotamine and methysergide
  • Medication used to treat Parkinson's disease

From: What Leads to Heart Failure? WebMD Medical Reference

SOURCES:

American Heart Association: "About Arrhythmia," "Alcohol and Heart Health," "Causes of Heart Failure," "Causes and Risks for Heart Failure," "How to Help Prevent Heart Disease -- At Any Age," "Illegal Drugs and Heart Disease," "Roles of Your Four Heart Valves," "Sleep Apnea and Heart Disease, Stroke," "What is Heart Failure?"

CDC: "Adult Obesity Facts," "Defining Adult Overweight and Obesity."

Circulation : "Drugs That May Cause or Exacerbate Heart Failure."

Cleveland Clinic: "Cardiomyopathy."

Heart Failure Matters: "Smoking."

Mayo Clinic: "Heart arrhythmia."

National Heart, Lung, and Blood Institute: "Description of High Blood Pressure," "What Is a Heart Attack?" "What Is Coronary Heart Disease?" "What Is Heart Valve Disease?"

National Institute of Diabetes and Digestive and Kidney Diseases: "What is Diabetes?"

NIH Senior Health: "Heart Failure: Causes and Risk Factors."

Reviewed by James Beckerman on May 17, 2019

SOURCES:

American Heart Association: "About Arrhythmia," "Alcohol and Heart Health," "Causes of Heart Failure," "Causes and Risks for Heart Failure," "How to Help Prevent Heart Disease -- At Any Age," "Illegal Drugs and Heart Disease," "Roles of Your Four Heart Valves," "Sleep Apnea and Heart Disease, Stroke," "What is Heart Failure?"

CDC: "Adult Obesity Facts," "Defining Adult Overweight and Obesity."

Circulation : "Drugs That May Cause or Exacerbate Heart Failure."

Cleveland Clinic: "Cardiomyopathy."

Heart Failure Matters: "Smoking."

Mayo Clinic: "Heart arrhythmia."

National Heart, Lung, and Blood Institute: "Description of High Blood Pressure," "What Is a Heart Attack?" "What Is Coronary Heart Disease?" "What Is Heart Valve Disease?"

National Institute of Diabetes and Digestive and Kidney Diseases: "What is Diabetes?"

NIH Senior Health: "Heart Failure: Causes and Risk Factors."

Reviewed by James Beckerman on May 17, 2019

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