Low Vitamin D Ups Heart Risk in Men

Study Shows Low Levels of Vitamin D Increase Risk of Heart Attack

Medically Reviewed by Elizabeth Klodas, MD, FACC on June 06, 2008

June 9, 2008 -- Drinking plenty of milk and basking in the sun may make a man less likely to have a heart attack.

New research published in the June 9 issue of Archives of Internal Medicine links low levels of vitamin D -- the "sunshine vitamin" -- with a higher risk of heart attack in men.

You can get vitamin D by drinking milk and eating foods fortified with the vitamin. But the body also makes vitamin D when exposed to sunlight. Studies have shown spikes in heart disease-related deaths at higher latitudes and during the winter months - areas and times of less daylight -- and decreases in such deaths at lower latitudes and during the summer.

For the current study, Edward Giovannucci, MD, ScD, of Harvard School of Public Health and Brigham and Women's Hospital, Boston, and colleagues reviewed medical records and blood samples of 454 men aged 40 to 75 who had heart attacks and survived or who had died of heart disease. They compared the information with similar data from 900 living men who did not have a history of heart disease, also noting the men's diet and lifestyle factors.

The researchers learned that men who had vitamin D levels of 15 ng/mL or less in their blood samples -- an indication of vitamin D deficiency -- had an increased risk for heart attack compared to those whose vitamin D level was considered sufficient (30 ng/mL). The twofold increased risk remained significant even when adjusting for other factors known to contribute to heart disease, such as high cholesterol, diabetes, high blood pressure, or a family history of heart disease.

Men with intermediate levels of vitamin D also were more likely to have a heart attack than those with adequate vitamin D levels.

"Vitamin D deficiency has been related to an increasing number of conditions and to total [death]. These results further support an important role for vitamin D in [heart attack] risk," the researchers say in a news release. "The present findings add further support that the current dietary requirements of vitamin D need to be increased to have an effect on [vitamin D] levels substantially large enough for potential health benefits."

The typical American diet often does not provide enough vitamin D since few foods naturally contain the vitamin. Eating plenty of vitamin-D-fortified foods, such as milk, cereals, and certain brands of orange juice, and getting lots of sunshine are key to maintaining adequate vitamin D levels.

Some people may need to take vitamin D supplements, especially those over 50. Older adults have a higher risk for vitamin D deficiency because aging itself makes it harder for the body to make vitamin D and convert it to a useable form.

Show Sources


News release, American Medical Association.

Giovannucci, E. Archives of Internal Medicine, June 9, 2008; vol 168: pp 1174-1180.

Office of Dietary Supplements: "Dietary Supplement Fact Sheet: Vitamin D."

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