How do promotility agents treat heartburn and reflux?
Promotility agents work by stimulating the muscles of the gastrointestinal tract to help prevent acids from staying in the stomach too long. They also strengthen the lower esophageal sphincter to help stop reflux into the esophagus. Metoclopramide (Reglan) is occasionally used to treat heartburn associated with GERD.
From: Prescription Drugs for Heartburn and Reflux WebMD Medical Reference
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