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Can elbasvir and grazoprevir (Zepatier) be used to treat my hepatitis C?

ANSWER

This once-a-day pill combination treats HCV types 1 or 4. It may also offer new hope for people with hepatitis C who also have cirrhosis, HIV, late-stage kidney disease, and other hard-to-treat health conditions. Like the other antivirals, the side effects are mild. You might have a slight headache, bellyache, or feel tired.

From: Hepatitis C Treatments WebMD Medical Reference

SOURCES:

Ryan Ford, MD, assistant professor of medicine, Division of Digestive Diseases, Emory University School of Medicine.

William D. Carey, MD, senior hepatologist, Department of Gastroenterology, Cleveland Clinic, Cleveland, Ohio.

HCV Advocate: “A Brief History of Hepatitis C.”

CDC: "Hepatitis C FAQs for Consumers." "Hepatitis C FAQs for Health Professionals."

Curry, M.P. , Dec. 31, 2015. New England Journal of Medicine

News Release, FDA.

FDA: "FDA Drug Safety Communication: FDA warns of serious liver injury risk with hepatitis C treatments Viekira Pak and Technivie." "FDA approves Mavyret for Hepatitis C." "Epclusa Prescribing Information." "FDA approves Viekira Pak to treat hepatitis C."

Feld, J. , Nov. 23, 2015. NEJM

HCV Advocate. "What is Cirrhosis?"

HCV New Drug Research: “ZEPATIER - Recommended Dosage and Durations, Drug Interactions, Side Effects, Clinical Studies.”

Hepatits C Online. "Peginterferon alfa-2a (Pegasys)." "Sofosbuvir-Velpatasvir-Voxilaprevir (Vosevi)." "Daclatasvir (Daklinza)." "Elbasvir-Grazoprevir (Zepatier)." "Ombitasvir-Paritaprevir-Ritonavir (Technivie)." "Sofosbuvir-Velpatasvir (Epclusa)."

Merck Connect. "Zepatier product site: Zepatier and You."

News Release, Gilead.

News Release, Merck.

Pharmacy Times: "Will Hepatitis C Virus Medication Costs Drop in the Years Ahead?"

Up-To-Date: “Direct-acting antivirals for the treatment of hepatitis C virus infection.”

U.S. Department of Veterans Affairs: "Hepatitis C Virus Genotypes and Quasispecies."

University of Washington: "Sofosbuvir (Sovaldi)."

Zeuzem, S. , July 7, 2015.   Annals of Internal Medicine

Reviewed by Laura J. Martin on October 14, 2018

SOURCES:

Ryan Ford, MD, assistant professor of medicine, Division of Digestive Diseases, Emory University School of Medicine.

William D. Carey, MD, senior hepatologist, Department of Gastroenterology, Cleveland Clinic, Cleveland, Ohio.

HCV Advocate: “A Brief History of Hepatitis C.”

CDC: "Hepatitis C FAQs for Consumers." "Hepatitis C FAQs for Health Professionals."

Curry, M.P. , Dec. 31, 2015. New England Journal of Medicine

News Release, FDA.

FDA: "FDA Drug Safety Communication: FDA warns of serious liver injury risk with hepatitis C treatments Viekira Pak and Technivie." "FDA approves Mavyret for Hepatitis C." "Epclusa Prescribing Information." "FDA approves Viekira Pak to treat hepatitis C."

Feld, J. , Nov. 23, 2015. NEJM

HCV Advocate. "What is Cirrhosis?"

HCV New Drug Research: “ZEPATIER - Recommended Dosage and Durations, Drug Interactions, Side Effects, Clinical Studies.”

Hepatits C Online. "Peginterferon alfa-2a (Pegasys)." "Sofosbuvir-Velpatasvir-Voxilaprevir (Vosevi)." "Daclatasvir (Daklinza)." "Elbasvir-Grazoprevir (Zepatier)." "Ombitasvir-Paritaprevir-Ritonavir (Technivie)." "Sofosbuvir-Velpatasvir (Epclusa)."

Merck Connect. "Zepatier product site: Zepatier and You."

News Release, Gilead.

News Release, Merck.

Pharmacy Times: "Will Hepatitis C Virus Medication Costs Drop in the Years Ahead?"

Up-To-Date: “Direct-acting antivirals for the treatment of hepatitis C virus infection.”

U.S. Department of Veterans Affairs: "Hepatitis C Virus Genotypes and Quasispecies."

University of Washington: "Sofosbuvir (Sovaldi)."

Zeuzem, S. , July 7, 2015.   Annals of Internal Medicine

Reviewed by Laura J. Martin on October 14, 2018

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When is glecaprevir and pibrentasvir (Mavyret) right to treat my hepatitis C?

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THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

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