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Which type of medication is most common to treat hep C?

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Medications known as direct acting antivirals, or DAAs, stop the hep c virus from making copies of itself. Some DAAs appear to work well on all hepatitis C genotypes. Others work on only one or some. Your doctor will probably prescribe some combination of these medications:

Some pills combine two of these drugs into one pill. You'll probably take these meds for anywhere from 8 to 12 weeks. But they may not be right for everyone because of things like cost or other illnesses. Your doctor might adjust or change your DAA treatment if you have:

  • Glecaprevir (Mavyret)
  • Sofosbuvir (Sovaldi)
  • Velpatasvir (Epclusa)
  • Hepatitis B
  • Kidney disease
  • Previous treatment for hep C
  • Cirrhosis
  • HIV
  • Pregnancy
  • Liver cancer (or if it's likely)
  • Liver transplant

SOURCES:

American Association for the Study of Liver Diseases: “Initial Treatment of Adults with HCV Infection,” “HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C.”

CDC: “Hepatitis C Questions and Answers for the Public.”

Infohep.org: “Hepatitis C treatment factsheet: Harvoni (sofosbuvir + ledipasvir).”

Hepatitis C Online: “Ledipasvir-Sofosbuvir (Harvoni).”

Merck Manual: “Overview of Chronic Hepatitis.”

The Hepatitis Trust: “HCV Genotypes,” “Hepatitis C Virus (HCV) Diagnostics Fact Sheet,” “Genotypes of hepatitis C,” “Harvoni.”

Treatment Action Group: “Hepatitis C Virus (HCV) Diagnostics Fact Sheet,” “Harvoni Fact Sheet.”

University of Maryland School of Pharmacy: “Transferability Of Economic

Evaluation Studies: Is There A Generally Accepted Alternative Price Benchmark To The Wac Price?”

U.S. Department of Veterans Affairs: “Viral Hepatitis and Liver Disease,” “Chronic Hepatitis C Virus (HCV) Infection: Treatment Considerations.”

Reviewed by Brunilda Nazario on June 01, 2020

SOURCES:

American Association for the Study of Liver Diseases: “Initial Treatment of Adults with HCV Infection,” “HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C.”

CDC: “Hepatitis C Questions and Answers for the Public.”

Infohep.org: “Hepatitis C treatment factsheet: Harvoni (sofosbuvir + ledipasvir).”

Hepatitis C Online: “Ledipasvir-Sofosbuvir (Harvoni).”

Merck Manual: “Overview of Chronic Hepatitis.”

The Hepatitis Trust: “HCV Genotypes,” “Hepatitis C Virus (HCV) Diagnostics Fact Sheet,” “Genotypes of hepatitis C,” “Harvoni.”

Treatment Action Group: “Hepatitis C Virus (HCV) Diagnostics Fact Sheet,” “Harvoni Fact Sheet.”

University of Maryland School of Pharmacy: “Transferability Of Economic

Evaluation Studies: Is There A Generally Accepted Alternative Price Benchmark To The Wac Price?”

U.S. Department of Veterans Affairs: “Viral Hepatitis and Liver Disease,” “Chronic Hepatitis C Virus (HCV) Infection: Treatment Considerations.”

Reviewed by Brunilda Nazario on June 01, 2020

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How does genotype affect treatment for hep C?

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