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How do direct renin inhibitors work for high blood pressure?

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To treat blood high blood pressure, direct renin inhibitors target the same process that ACE inhibitors and ARBs do, so your blood vessels don't tighten up. But they work on the enzyme renin instead. They stop it from triggering reactions before the hormone gets made.

Aliskiren (Tekturna) is a direct renin inhibitor.

American Academy of Family Physicians: "Blood Pressure Medicines and High Blood Pressure: Things You Can Do to Help Lower Yours."

American Heart Association: "Types of Blood Pressure Medications."

National Heart, Lung, and Blood Institute: "High Blood Pressure."

National Library of Medicine.

Mayo Clinic: "High blood pressure (hypertension): Central-acting agents."

Reviewed by James Beckerman on May 2, 2017

American Academy of Family Physicians: "Blood Pressure Medicines and High Blood Pressure: Things You Can Do to Help Lower Yours."

American Heart Association: "Types of Blood Pressure Medications."

National Heart, Lung, and Blood Institute: "High Blood Pressure."

National Library of Medicine.

Mayo Clinic: "High blood pressure (hypertension): Central-acting agents."

Reviewed by James Beckerman on May 2, 2017

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How do calcium channel blockers work for high blood pressure?

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