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How do drugs for Crohn's disease affect pregnancy?

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If you are on steroids, you should not get pregnant. If you are taking a corticosteroid such as prednisone or another steroid and do get pregnant, your doctor will prescribe the smallest possible dose. If you are breastfeeding while taking steroids in moderate to high doses, your baby should be monitored by a pediatrician.

Drugs that affect the immune system are called immunomodulators and immunosuppressives. These drugs do not seem to cause problems during pregnancy when they are used in standard dosages. The exception is methotrexate. Methotrexate should not be taken if you are pregnant. Nor should it be taken by either a man or a woman who is trying to conceive. Methotrexate can cause the death of the fetus. It can also cause congenital abnormalities. If you are taking methotrexate, you also should not breastfeed.

From: Crohn's Disease and Pregnancy WebMD Medical Reference

Reviewed by Minesh Khatri on September 17, 2019

Medically Reviewed on 9/17/2019

SOURCES:

Crohn's and Colitis Foundation of America: "IBD and Pregnancy: What You Need to Know."

FDA. “FDA approves Amjevita, a biosimilar to Humira.”

National Digestive Disease Information Clearinghouse: "Crohn's Disease."

Reviewed by Minesh Khatri on September 17, 2019

SOURCES:

Crohn's and Colitis Foundation of America: "IBD and Pregnancy: What You Need to Know."

FDA. “FDA approves Amjevita, a biosimilar to Humira.”

National Digestive Disease Information Clearinghouse: "Crohn's Disease."

Reviewed by Minesh Khatri on September 17, 2019

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Are biologic drugs for Crohn's disease safe to use during pregnancy?

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