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How does Crohn's disease cause inflammation?

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Crohn’s is a disorder of uncertain etiology. It has often been thought of as an autoimmune disease but research suggests that the chronic inflammation may not be due to the immune system attacking the body itself, but rather a result of the immune system attacking harmless virus, bacteria or food in the gut causing inflammation that leads to bowel injury. Crohn's disease can cause other parts of the body to become inflamed (due to chronic inflammatory activity) including the joints, eyes, mouth, and skin. In addition, gallstones and kidney stones may also develop as a result of Crohn's disease.

From: Crohn’s Disease Overview WebMD Medical Reference

SOURCES: 

Crohn's & Colitis Foundation of America. "Crohn's Diagnosis & Testing."

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

National Digestive Diseases Information Clearinghouse.

Uptodate.com. "Overview of the medical management of severe or refractory Crohn disease in adults."

 

Reviewed by Minesh Khatri on June 21, 2018

SOURCES: 

Crohn's & Colitis Foundation of America. "Crohn's Diagnosis & Testing."

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

National Digestive Diseases Information Clearinghouse.

Uptodate.com. "Overview of the medical management of severe or refractory Crohn disease in adults."

 

Reviewed by Minesh Khatri on June 21, 2018

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What do children with Crohn's disease experience?

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