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How does the immune system in a person with Crohn's disease work?

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For some reason, people with Crohn's disease have an immune system that reacts inappropriately. The immune system may be defending the body against helpful microbes by mistake -- or, for some other reason, the inflammatory response simply will not stop. Either way, over time, this chronic inflammation in the digestive system can result in ulcers and other injuries to the intestines.

From: What Causes Crohn’s Disease? WebMD Medical Reference

SOURCES:

National Digestive Diseases Information Clearinghouse: "Crohn's Disease."

Crohn's and Colitis Foundation of America: "About Crohn's Disease."

Merck: (online version): "The Immune Response: Defenses Against Infection." Merck Manual: Home Edition for Patients and Caregivers

American College of Gastroenterology: "Inflammatory Bowel Disease."

Reviewed by Minesh Khatri on October 25, 2017

SOURCES:

National Digestive Diseases Information Clearinghouse: "Crohn's Disease."

Crohn's and Colitis Foundation of America: "About Crohn's Disease."

Merck: (online version): "The Immune Response: Defenses Against Infection." Merck Manual: Home Edition for Patients and Caregivers

American College of Gastroenterology: "Inflammatory Bowel Disease."

Reviewed by Minesh Khatri on October 25, 2017

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Who is most likely to have Crohn's disease?

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