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Why do doctors prescribe mesalamine for Crohn's disease, and how does it impact your heart?

ANSWER

Mesalamine (Apriso, Asacol, Delzicol, Lialda, Pentasa) is a drug doctors often try early on to treat symptoms of Crohn's disease. It can inflame your heart muscle, a condition your doctor calls myocarditis. Symptoms go away when you stop taking it.

SOURCES:

Singh, S. National Review of Gastroenterology Hepatology, January 2015.

American Heart Association: “Atherosclerosis.”

Ruisi, P. Journal of Clinical Medical Research, published online, Feb. 9, 2015.

Andersen, N. World Journal of Gastrointestinal Pathophysiology, Aug. 15, 2014.

Royal College of Nursing: “Understanding VTE.”

Kristensen, S.L. British Medical Journal, November 2014.

Kristensen, S.L. Circulation, published online, July 22, 2014.

Kristensen, S.L. PLoS One, Feb. 15, 2013.

Myocarditis Foundation: “About Myocarditis.”

Sorleto, M. Case Reports in Cardiology, 2015.

Gandhi, S. The American Journal of Medicine, published online, July 26, 2012.

Reviewed by Neha Pathak on October 15, 2020

SOURCES:

Singh, S. National Review of Gastroenterology Hepatology, January 2015.

American Heart Association: “Atherosclerosis.”

Ruisi, P. Journal of Clinical Medical Research, published online, Feb. 9, 2015.

Andersen, N. World Journal of Gastrointestinal Pathophysiology, Aug. 15, 2014.

Royal College of Nursing: “Understanding VTE.”

Kristensen, S.L. British Medical Journal, November 2014.

Kristensen, S.L. Circulation, published online, July 22, 2014.

Kristensen, S.L. PLoS One, Feb. 15, 2013.

Myocarditis Foundation: “About Myocarditis.”

Sorleto, M. Case Reports in Cardiology, 2015.

Gandhi, S. The American Journal of Medicine, published online, July 26, 2012.

Reviewed by Neha Pathak on October 15, 2020

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What kinds of OTC medications may ease symptoms of Crohn's disease?

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