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How do medicines work to treat Crohn’s disease and ulcerative colitis (UC)?

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Medicines can get inflammation caused by Crohn’s disease and ulcerative colitis under control:

5-ASAs work on the lining of your GI tract to lower inflammation. They work best in the colon. You might take them to treat an ulcerative colitis flare, or as a maintenance treatment to prevent relapses of the disease.

Steroids curb the immune system to treat ulcerative colitis. Because of side effects, you probably won't stay on them for a long time.

SOURCES:

Cleveland Clinic: “Why You Should Pay Attention to Chronic Inflammation.”

Crohn’s and Colitis Foundation of America: “What are Crohn’s & Colitis?” "Crohn’s Diagnosis & Testing." “Diagnosing Crohn's Disease and Ulcerative Colitis” “Surgery for Crohn’s Disease & Colitis?”

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

Itzkowitz, S. Inflammatory Bowel Diseases, March 2005.

Mayo Clinic: “Inflammatory Bowel Disease.”

Medscape: “Ulcerative Colitis Differential Diagnoses.”

PubMedHealth: “Colon (Bowel.)”

UCLA Division of Digestive Disorders: “Ulcerative Colitis vs. Crohn's Disease.”

UpToDate: “Patient information: Ulcerative colitis (Beyond the Basics).” “Patient information: Crohn Disease (Beyond the Basics)." "Clinical manifestations, diagnosis and prognosis of Crohn disease in adults." “Colorectal cancer surveillance in inflammatory bowel disease.”

Reviewed by Melinda Ratini on September 4, 2020

SOURCES:

Cleveland Clinic: “Why You Should Pay Attention to Chronic Inflammation.”

Crohn’s and Colitis Foundation of America: “What are Crohn’s & Colitis?” "Crohn’s Diagnosis & Testing." “Diagnosing Crohn's Disease and Ulcerative Colitis” “Surgery for Crohn’s Disease & Colitis?”

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

Itzkowitz, S. Inflammatory Bowel Diseases, March 2005.

Mayo Clinic: “Inflammatory Bowel Disease.”

Medscape: “Ulcerative Colitis Differential Diagnoses.”

PubMedHealth: “Colon (Bowel.)”

UCLA Division of Digestive Disorders: “Ulcerative Colitis vs. Crohn's Disease.”

UpToDate: “Patient information: Ulcerative colitis (Beyond the Basics).” “Patient information: Crohn Disease (Beyond the Basics)." "Clinical manifestations, diagnosis and prognosis of Crohn disease in adults." “Colorectal cancer surveillance in inflammatory bowel disease.”

Reviewed by Melinda Ratini on September 4, 2020

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What drugs are used to treat Crohn’s disease and ulcerative colitis (UC)?

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