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Do ulcerative colitis and Crohn's disease affect the same parts of the gut?

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Ulcerative colitis affects only the inner lining of your colon, also called the large intestine. But with Crohn’s disease, inflammation can happen anywhere in your digestive tract, from your mouth to your anus. And it generally affects all the layers of the bowel walls, not just the inner lining. Also, people with Crohn’s disease often have healthy areas in between inflamed spots. But with ulcerative colitis, there are no healthy areas in between inflamed spots.

SOURCES:

Cleveland Clinic: “Why You Should Pay Attention to Chronic Inflammation.”

Crohn’s and Colitis Foundation of America: “What are Crohn’s & Colitis?” "Crohn’s Diagnosis & Testing." “Diagnosing Crohn's Disease and Ulcerative Colitis” “Surgery for Crohn’s Disease & Colitis?”

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

Itzkowitz, S. March 2005. Inflammatory Bowel Diseases,

Mayo Clinic: “Inflammatory Bowel Disease.”

Medscape: “Ulcerative Colitis Differential Diagnoses.”

PubMedHealth: “Colon (Bowel.)”

UCLA Division of Digestive Disorders: “Ulcerative Colitis vs. Crohn's Disease.”

UpToDate: “Patient information: Ulcerative colitis (Beyond the Basics).” “Patient information: Crohn Disease (Beyond the Basics)." "Clinical manifestations, diagnosis and prognosis of Crohn disease in adults." “Colorectal cancer surveillance in inflammatory bowel disease.”

Reviewed by Melinda Ratini on September 04, 2018

SOURCES:

Cleveland Clinic: “Why You Should Pay Attention to Chronic Inflammation.”

Crohn’s and Colitis Foundation of America: “What are Crohn’s & Colitis?” "Crohn’s Diagnosis & Testing." “Diagnosing Crohn's Disease and Ulcerative Colitis” “Surgery for Crohn’s Disease & Colitis?”

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

Itzkowitz, S. March 2005. Inflammatory Bowel Diseases,

Mayo Clinic: “Inflammatory Bowel Disease.”

Medscape: “Ulcerative Colitis Differential Diagnoses.”

PubMedHealth: “Colon (Bowel.)”

UCLA Division of Digestive Disorders: “Ulcerative Colitis vs. Crohn's Disease.”

UpToDate: “Patient information: Ulcerative colitis (Beyond the Basics).” “Patient information: Crohn Disease (Beyond the Basics)." "Clinical manifestations, diagnosis and prognosis of Crohn disease in adults." “Colorectal cancer surveillance in inflammatory bowel disease.”

Reviewed by Melinda Ratini on September 04, 2018

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Where does the inflammation occur in Crohn’s disease and ulcerative colitis (UC)?

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