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What blood tests are used for Crohn’s disease and ulcerative colitis (UC)?

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Scientists are working to make several blood tests better at helping diagnose ulcerative colitis and Crohn’s. They check on levels of certain antibodies found in the blood. Two of these are:

  • pANCA (perinuclear anti-neutrophil antibodies)
  • ASCA (anti-Saccharomyces Cerevisiae antibody)

SOURCES:

Cleveland Clinic: “Why You Should Pay Attention to Chronic Inflammation.”

Crohn’s and Colitis Foundation of America: “What are Crohn’s & Colitis?” "Crohn’s Diagnosis & Testing." “Diagnosing Crohn's Disease and Ulcerative Colitis” “Surgery for Crohn’s Disease & Colitis?”

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

Itzkowitz, S. Inflammatory Bowel Diseases, March 2005.

Mayo Clinic: “Inflammatory Bowel Disease.”

Medscape: “Ulcerative Colitis Differential Diagnoses.”

PubMedHealth: “Colon (Bowel.)”

UCLA Division of Digestive Disorders: “Ulcerative Colitis vs. Crohn's Disease.”

UpToDate: “Patient information: Ulcerative colitis (Beyond the Basics).” “Patient information: Crohn Disease (Beyond the Basics)." "Clinical manifestations, diagnosis and prognosis of Crohn disease in adults." “Colorectal cancer surveillance in inflammatory bowel disease.”

Reviewed by Melinda Ratini on September 4, 2020

SOURCES:

Cleveland Clinic: “Why You Should Pay Attention to Chronic Inflammation.”

Crohn’s and Colitis Foundation of America: “What are Crohn’s & Colitis?” "Crohn’s Diagnosis & Testing." “Diagnosing Crohn's Disease and Ulcerative Colitis” “Surgery for Crohn’s Disease & Colitis?”

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

Itzkowitz, S. Inflammatory Bowel Diseases, March 2005.

Mayo Clinic: “Inflammatory Bowel Disease.”

Medscape: “Ulcerative Colitis Differential Diagnoses.”

PubMedHealth: “Colon (Bowel.)”

UCLA Division of Digestive Disorders: “Ulcerative Colitis vs. Crohn's Disease.”

UpToDate: “Patient information: Ulcerative colitis (Beyond the Basics).” “Patient information: Crohn Disease (Beyond the Basics)." "Clinical manifestations, diagnosis and prognosis of Crohn disease in adults." “Colorectal cancer surveillance in inflammatory bowel disease.”

Reviewed by Melinda Ratini on September 4, 2020

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What are blood test findings in Crohn’s disease and ulcerative colitis (UC)?

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